Latest news articles

Added 1 day ago Drug news

Mesoblast Ltd makes rolling submission to FDA for remestemcel-L in children with steroid-refractory acute graft versus host disease.

Mesoblast Limited announced that the FDA has agreed that Mesoblast can submit on a rolling basis a Biologics License Application...

Added 1 month ago Drug news

UVADEX sterile solution and THERAKOS CELLEX Photopheresis system interim phase III results for Graft-versus-Host Disease . - Mallinckrodt

Mallinckrodt Pharmaceuticals announced interim analysis results of its company-sponsored, Phase III, single-arm, open-label, multi-center study assessing the efficacy of treating...

Added 2 months ago Drug news

FDA extends PDUFA date for Jakavi to treat acute graft-versus-host disease.- Incyte + Novartis

Incyte announced that the FDA has extended the review period for the supplemental New Drug Application (sNDA) for ruxolitinib (Jakafi)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

EASL Clinical Practice Guidelines: Liver transplantation

This Clinical Practice Guideline (CPG) has been developed to assist physicians and other healthcare providers during the evaluation process of candidates for LT and to help them in the correct management of patients after LT.

Added 3 years ago

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Journal articles

Steatosis in Liver Transplantation: Current Limitations and Future Strategies.

This review focuses on the current and potential future treatment of NASH and the clinical practice in fatty liver transplantation, highlights its limitations and optimal allocation, and summarizes the advances of experimental...

Added 24 days ago

Bone marrow versus peripheral blood as a graft source for haploidentical donor transplantation in adults using post-transplant cyclophosphamide-A systematic review and meta-analysis.

Background: Peripheral-blood (PB) and bone marrow (BM) are both widely used in hematopoietic stem cell transplantation (HSCT). However, it is unclear whether PB or BM produces a more satisfactory outcome in haploidentical HSCT...

Added 24 days ago

Markers of graft microvascular endothelial injury may identify harmful donor specific anti-HLA antibodies and predict kidney allograft loss.

Graft microvasculature is a major target of donor-specific antibodies (DSA) and endothelial damage is a direct evidence of antibody-mediated rejection (ABMR). Using immunohistochemistry, we analyzed the expression...

Added 24 days ago

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Clinical trials

Letermovir (MK-8228) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001)

The study evaluated the efficacy and safety of letermovir (MK-8228) for the prevention of clinically-significant CMV infection in adult, CMV-seropositive recipients of allogeneic hematopoietic stem cell transplant (HSCT).

Added 1 year ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

CME

Starting patients on anticoagulants in secondary care: how to do it

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