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Added 13 days ago Drug news

FDA extends PDUFA date for Jakavi to treat acute graft-versus-host disease.- Incyte + Novartis

Incyte announced that the FDA has extended the review period for the supplemental New Drug Application (sNDA) for ruxolitinib (Jakafi)...

Added 2 months ago Drug news

FDA approves Envarsus XR for organ rejection in de novo kidney transplant.- Veloxis Pharma.

Veloxis Pharmaceuticals announced that the FDA approved a new indication for Envarsus XR (tacrolimus extended-release tablets) to prevent organ rejection...

Added 3 months ago Drug news

FDA grants priority review to Jakafi which is filed for acute graft-versus-host-disease.- Incyte Corp.

The FDA has accepted for Priority Review its supplemental New Drug Application (sNDA) for Jakafi(ruxolitinib), from Incyte Corp., for the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

EASL Clinical Practice Guidelines: Liver transplantation

This Clinical Practice Guideline (CPG) has been developed to assist physicians and other healthcare providers during the evaluation process of candidates for LT and to help them in the correct management of patients after LT.

Added 3 years ago

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Journal articles

Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation.

Background: Cytomegalovirus (CMV) infection remains a common complication after allogeneic hematopoietic-cell transplantation. Letermovir is an antiviral drug that inhibits the CMV-terminase complex.

Added 1 year ago

Letermovir: First Global Approval.

Letermovir (Prevymis™) is an orally or intravenously administered cytomegalovirus (CMV) DNA terminase complex inhibitor being developed by Merck & Co., Inc., under a global license from AiCuris Anti-infective Cures GmbH.

Added 1 year ago

Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative condition where loss of motor neurons within the brain and spinal cord leads to muscle atrophy, weakness, paralysis and ultimately death...

Added 1 year ago

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Clinical trials

Letermovir (MK-8228) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001)

The study evaluated the efficacy and safety of letermovir (MK-8228) for the prevention of clinically-significant CMV infection in adult, CMV-seropositive recipients of allogeneic hematopoietic stem cell transplant (HSCT).

Added 1 year ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

CME

Starting patients on anticoagulants in secondary care: how to do it

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