Latest news articles

Added 1 year ago Drug news

In updated guidance NICE does not recommend Caprelsa in medullary thyroid cancer.- Genzyme/Sanofi.

In updated guidance based on its latest review, NICE has announced that Caprelsa (vandetanib), from Genzyme/Sanofi, is not recommended, within...

Added 1 year ago Drug news

FDA approves Tafinlar + Mekinist for anaplastic thyroid cancer.- Novartis.

The FDA has approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, from Novartis, for the treatment of anaplastic thyroid cancer...

Added 2 years ago Drug news

Eisai + Merck Inc., to collaborate on development and marketing of Lenvima as monotherapy and with Keytruda.

Eisai Co., Ltd. and Merck & Co., Inc., announced that the companies have agreed upon a strategic collaboration for the...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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CDK 4/6 inhibitors in metastatic breast cancer

CDK 4/6 inhibitors in metastatic breast cancer

The CDK 4/6 Inhibitors in Metastatic Breast Cancer Learning Zone provides insights and information for metastatic breast cancer (mBC) and CDK 4/6 signalling. This includes the burden and pathophysiology of the disease, the role of CDK 4/6 in cell proliferation and an overview of the CDK 4/6 inhibitors that have been approved for the management of mBC.

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European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS

Thyroid ultrasound (US) is a key examination for the management of thyroid nodules. Thyroid US is easily accessible, noninvasive, and cost-effective, and is a mandatory step in the workup of thyroid nodules.

Added 1 year ago

Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

This guideline covers incidence and epidemiology, diagnosis, staging and management of differentiated thyroid cancer, medullary thyroid cancer, poorly differentiated thyroid carcinoma and anaplastic thyroid cancer.

Added 7 years ago

2012 European Thyroid Association Guidelines for Metastatic Medullary Thyroid Cancer

These 21 recommendations focus on MTC patients with distant metastases and a detailed follow-up protocol of patients with biochemical or imaging evidence of disease, selection criteria for treatment, and treatment modalities...

Added 7 years ago

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Journal articles

Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo.

The antitumor activity of vandetanib [a multiple signal transduction inhibitor including the RET tyrosine kinase, epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) receptor (VEGFR),...

Added 1 year ago

Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib.

Purpose: Vandetanib is well-tolerated in patients with advanced medullary thyroid carcinoma (MTC). Long-term outcomes and mechanisms of MTC progression have not been reported previously.

Added 1 year ago

Association of Parathyroid Hormone Level With Postthyroidectomy Hypocalcemia: A Systematic Review.

Importance: There has been an increased interest in measuring parathyroid hormone (PTH) levels as an early predictive marker for the development of hypocalcemia after total thyroidectomy.

Added 2 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.


Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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