Latest news articles

Added 14 days ago Drug news

Results of phase III SOLO3 trial of Lynparza for patients with germline BRCA1/2-mutated (gBRCAm) advanced ovarian cancer.

AstraZeneca and MSD Inc., presented full results from the Phase III SOLO3 trial which compared Lynparza (olaparib) with physician’s choice...

Added 15 days ago Drug news

Results from POLO trial of Lynparza as monotherapy for maintenance for BRCA mutated pancreatic cancer.

AstraZeneca and MSD Inc., announced detailed results from the Phase III POLO trial at the 2019 American Society of Clinical...

Added 1 month ago Drug news

FDA requires new phase III trial for mirvetuximab soravtansine for patients with (FR alpha)-positive

ImmunoGen, Inc.,has announced the FDA has recommended that the Company conduct a new Phase III randomized trial to evaluate the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Biosimilars in Oncology Knowledge Centre

Biosimilars in Oncology Knowledge Centre

What are biologics and how do they differ from small molecule medicines? Discover more about their development, as well as the manufacturing and regulatory processes in the Biosimilars in Oncology Knowledge Centre.

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Guidelines

Management of epithelial ovarian cancer

This guideline provides recommendations based on current evidence for best practice in screening and the role of prophylactic salpingo-oophorectomy; diagnosis; surgical management; chemotherapy; follow up; management...

Added 5 years ago

Newly diagnosed and relapsed epithelial ovarian carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up on non-epithelial ovarian cancer covers diagnosis and pathology/molecular biology, staging and risk assessment, treatment plan...

Added 5 years ago

Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up on non-epithelial ovarian cancer covers diagnosis and pathology/molecular biology, staging and risk assessment, treatment plan for early and advanced stages...

Added 7 years ago

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Journal articles

Rucaparib: An emerging parp inhibitor for treatment of recurrent ovarian cancer.

Recently, Poly-ADP-Ribose Polymerase (PARP) inhibitors are one of the most intensively studied group of antiblastic agents for the management of recurrent ovarian cancer.

Added 1 year ago

Rucaparib: a novel PARP inhibitor for BRCA advanced ovarian cancer.

Rucaparib is a potent small-molecule inhibitor of poly (ADP-ribose) polymerase (PARP) proteins (PARP-1, PARP-2 and PARP-3) that play an important role in repairing DNA damage and maintaining genomic stability.

Added 1 year ago

Rucaparib: a new treatment option for ovarian cancer.

Areas covered: In this review, the authors discuss the efficacy and toxicity of rucaparib either as a single agent or as a maintenance treatment for ovarian cancer.

Added 1 year ago

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Clinical trials

PH3 Study of IMGN853 vs Investigator's Choice of Chemotherapy in Women With FRa+ Adv. EOC, Primary Peritoneal or Fallopian Tube Cancer (FORWARD I)

This is a Phase 3, open label, randomized study designed to compare the safety and efficacy of IMGN853 to that of selected single-agent chemotherapy (Investigator's choice) in women with platinum-resistant FR-alpha positive advanced...

Added 2 years ago

A Study of Rucaparib as Switch Maintenance Following Platinum-Based Chemotherapy in Patients With Platinum-Sensitive, High-Grade Serous or Endometrioid Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer (ARIEL3)

Patients enrolled into this study will be stratified into 3 groups based on gene mutations identified in their tumor tissue. The purpose of this study is to evaluate patient response to maintenance treatment with rucaparib...

Added 6 years ago

A Study of Rucaparib in Patients With Platinum-Sensitive, Relapsed, High-Grade Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer (ARIEL2)

The purpose of this study is to determine which patients with ovarian, fallopian tube, and primary peritoneal cancer will best respond to treatment with rucaparib.

Added 1 year ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Ovarian cancer: clinical review

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MIMS Learning - Monthly Index of Medical Specialities
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