Latest news articles

Added 2 days ago Drug news

Tecentriq + Avastin combination in Phase III trial to treat Liver Cancer.- Genentech + Roche.

Genentech now reports that earlier this year, Genentech initiated IMbrave150 (NCT03434379), an open-label, multicenter, randomized Phase III study investigating the...

Added 7 days ago Drug news

NEJM publishes results of CELESTIAL trial of Cabometyx in patients with previously treated advanced hepatocellular carcinoma.- Ipsen + Exelixis.

Ipsen announced that The New England Journal of Medicine (NEJM) published results from the CELESTIAL phase III pivotal trial of...

Added 9 days ago Drug news

Keytruda filed and granted priority review with FDA for liver cancer.- Merck Inc.

The FDA has accepted and granted priority review for a new supplemental Biologics License Application (sBLA) seeking approval for Keytruda...

Search all news articles for Cancer of liver and bile duct
 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

Load more

Guidelines

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

The following Clinical Practice Guidelines will give up-to-date advice for the clinical management of patients with hepatocellular carcinoma, as well as providing an in-depth review of all the relevant data leading to the conclusions herein.

Added 1 month ago

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

These guidelines focus on diagnosis and pathology/molecular biology, staging and risk assessment and management of biliary cancer including follow-up and long-term implications.

Added 7 years ago

EASL Clinical Practice Guidelines: Liver transplantation

This Clinical Practice Guideline (CPG) has been developed to assist physicians and other healthcare providers during the evaluation process of candidates for LT and to help them in the correct management of patients after LT.

Added 2 years ago

Search all guidelines for Cancer of liver and bile duct
 

Journal articles

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma.

Cabozantinib inhibits tyrosine kinases, including vascular endothelial growth factor receptors 1, 2, and 3, MET, and AXL, which are implicated in the progression of hepatocellular carcinoma and the development of resistance...

Added 5 days ago

The role of liver resection in the management of intermediate and advanced stage hepatocellular carcinoma. A systematic review.

Background: The ideal management for patients with intermediate and advanced stage hepatocellular carcinoma (HCC) is controversial. The main purpose of this systematic review is to examine the role of liver resection...

Added 6 months ago

Interaction of margin status and tumour burden determines survival after resection of colorectal liver metastases: A retrospective cohort study.

Purpose: We sought to determine the impact of surgical margin status on overall survival (OS) and recurrence pattern stratified by tumor burden.

Added 6 months ago

Search all journal articles for Cancer of liver and bile duct
 

Clinical trials

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 8 months ago

Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394)

The purpose of this study is to determine the efficacy and safety of pembrolizumab or placebo given with best supportive care (BSC) in Asian participants with previously systemically treated advanced hepatocellular carcinoma (HCC).

Added 5 days ago

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 1 year ago

Search all clinical trials for Cancer of liver and bile duct
 
Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.