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Added 4 days ago Drug news

Cabometyx filed with FDA for treating previously treated advanced hepatocellular carcinoma.- Exelixis.

Exelixis has completed the submission of a supplemental New Drug Application (sNDA) to the FDA for Cabometyx (cabozantinib) tablets as...

Added 1 month ago Drug news

Phase III REFLECT study of Lenvima in hepatocellular carcinoma published in The Lancet.- Eisai.

Eisai Inc. announced that the positive results of a Phase III study (REFLECT study, Study 304) of Lenvima (lenvatinib mesylate)...

Added 1 month ago Drug news

Successful Phase II trial of Keytruda in patients with advanced liver cancer.

Merck announced findings from the registrational phase II KEYNOTE-224 trial investigating the use of Keytruda (pembrolizumab).

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.



See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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BSG guidelines for the diagnosis and treatment of cholangiocarcinoma

This is the first update since then and is based on a comprehensive review of the recent literature, including data from randomised controlled trials, systematic reviews, meta-analyses, cohort, prospective and retrospective studies.

Added 5 years ago

Erratum to: EASL–EORTC Clinical Practice Guidelines: Management of hepatocellular carcinoma

Fig. 3 was incomplete for BCLC stage A, and it has been corrected as per below. Patients at BCLC stage...

Added 5 years ago

Hepatocellular carcinoma: ESMO–ESDO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best...

Added 5 years ago

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Journal articles

The role of liver resection in the management of intermediate and advanced stage hepatocellular carcinoma. A systematic review.

Background: The ideal management for patients with intermediate and advanced stage hepatocellular carcinoma (HCC) is controversial. The main purpose of this systematic review is to examine the role of liver resection...

Added 2 months ago

Interaction of margin status and tumour burden determines survival after resection of colorectal liver metastases: A retrospective cohort study.

Purpose: We sought to determine the impact of surgical margin status on overall survival (OS) and recurrence pattern stratified by tumor burden.

Added 2 months ago

CEACAM1 is associated with recurrence after hepatectomy for colorectal liver metastasis.

Background: Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is re-expressed at the invasion front of colorectal cancer. CEACAM1 expression at metastatic sites remains to be investigated.

Added 3 months ago

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Clinical trials

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 4 months ago

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 10 months ago

Efficacy and Tolerability of Hemopatch After Hepatic Resection

• Previous in vitro and in vivo studies detected the Hemopatch Sealing Hemostat® to be a new versatile, self-adhering hemostatic sealing pad consisting of a polyethylene glycol-coated collagen.

Added 4 months ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.