Latest news articles

Added 4 hours ago Drug news

EU approves Cabometyx for liver cancer.- Ipsen + Exelixis.

Exelixis announced that its partner Ipsen received approval from the European Commission (EC) for Cabometyx (cabozantinib) tablets as a monotherapy...

Added 1 day ago Drug news

TAPPAS phase III trial shows ApoStream effective in capturing tumour cells in angiosarcoma.- Precision for Medicine.

Precision for Medicine and TRACON Pharmaceuticals announced the publication of biomarker results from the TAPPAS phase III clinical trial that...

Added 5 days ago Drug news

FDA gives accelerated approval to Keytruda for previously treated hepatocellular carcinoma.- Merck Inc.

Merck Inc announced that the FDA has approved Keytruda (pembrolizumab), Merck’s anti-PD-1 therapy, for the treatment of patients with hepatocellular...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

The following Clinical Practice Guidelines will give up-to-date advice for the clinical management of patients with hepatocellular carcinoma, as well as providing an in-depth review of all the relevant data leading to the conclusions herein.

Added 4 months ago

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

These guidelines focus on diagnosis and pathology/molecular biology, staging and risk assessment and management of biliary cancer including follow-up and long-term implications.

Added 7 years ago

EASL Clinical Practice Guidelines: Liver transplantation

This Clinical Practice Guideline (CPG) has been developed to assist physicians and other healthcare providers during the evaluation process of candidates for LT and to help them in the correct management of patients after LT.

Added 2 years ago

Search all guidelines for Cancer of liver and bile duct
 

Journal articles

Sorafenib for Advanced Hepatocellular Carcinoma: A Real-Life Experience.

The study aimed to describe real-life experience in advanced HCC treatment with SOR at a university hospital in Brazil and to estimate the number of patients with indication of second-line therapy.

Added 3 months ago

Systemic therapy for intermediate and advanced hepatocellular carcinoma: Sorafenib and beyond.

The hepatocellular carcinoma (HCC) treatment landscape changed a decade ago, with sorafenib demonstrating survival benefit in the first-line setting and becoming the first systemic therapy to be approved for HCC.

Added 3 months ago

Regorafenib in hepatocellular carcinoma: latest evidence and clinical implications.

Over the past ten years, sorafenib, a multikinase inhibitor, has been the only systemic agent approved for first-line treatment of patients with unresectable hepatocellular carcinoma (HCC).

Added 3 months ago

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Clinical trials

A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma [IMbrave150]

This study will evaluate the efficacy and safety of atezolizumab in combination with bevacizumab compared with sorafenib in participants with locally advanced or metastatic Hepatocellular Carcinoma (HCC)...

Added 3 months ago

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 1 year ago

Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394)

The purpose of this study is to determine the efficacy and safety of pembrolizumab or placebo given with best supportive care (BSC) in Asian participants with previously systemically treated advanced hepatocellular carcinoma (HCC).

Added 3 months ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.