Latest news articles

Added 8 days ago Drug news

Positive Phase III TIVO-3 trial of tivozanib to treat refractory advanced or metastatic renal cell carcinoma.- Aveo Oncology.

AVEO Oncology announced positive topline results from the primary analysis of the TIVO-3 trial, the Company’s Phase III randomized, controlled,...

Added 28 days ago Drug news

Phase III KEYNOTE-426 trial of Keytruda + Inlyta meets primary endpoints in renal cell carcinoma.- Merck Inc. + Pfizer.

Merck Inc announced that the pivotal Phase III KEYNOTE-426 trial investigating Keytruda (pembrolizumab), Merck’s anti-PD-1 therapy, in combination with Inlyta...

Added 2 months ago Drug news

Bavencio + Inylta positive results in Javelin Renal 101 study for renal cell carcinoma -Merck KGaA + Pfizer

Merck KGaA and Pfizer Inc. announced positive top-line results from the pivotal Phase III JAVELIN Renal 101 study evaluating Bavencio...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

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Guidelines

Guidelines on Renal Cell Carcinoma

The European Association of Urology (EAU) Renal Cell Cancer (RCC) Guidelines Panel has compiled these clinical guidelines to provide urologists with evidence-based information and recommendations for the management of renal cell cancer.

Added 2 years ago

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Kidney cancer accounts for 5% and 3% of all adult malignancies in men and women, respectively, thus representing the 7th most common cancer in men and the 10th most common cancer in women.

Added 4 years ago

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Journal articles

Management of Adverse Events Associated with Cabozantinib Therapy in Renal Cell Carcinoma.

This review aims to provide appropriate guidance that will minimize the impact of adverse events and help to maximize the utility of this agent in patients with advanced renal cell carcinoma.

Added 4 months ago

Efficacy of tivozanib treatment after sorafenib in patients with advanced renal cell carcinoma: crossover of a phase 3 study.

Background: Tivozanib is a selective inhibitor of vascular endothelial growth factor receptors 1, 2 and 3 tyrosine kinases. This open-label, crossover clinical study (AV-951-09-902) provided access to tivozanib for patients...

Added 7 months ago

Tivozanib: a new treatment option for renal cell carcinoma.

Tivozanib is a tyrosine kinase inhibitor that targets all vascular endothelial growth factor receptors (VEGFRs), causing inhibition of angiogenesis. It has recently been approved by the European Medicines Agency (EMA)...

Added 7 months ago

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Clinical trials

Cabozantinib Versus Sunitinib for Metastatic Variant Histology Renal Cell Carcinoma

The goal of this clinical research study is to compare the safety and effectiveness of cabozantinib and sunitinib when given to patients with metastatic (has spread) variant histology renal cell carcinoma (vhRCC), a type of kidney cancer.

Added 3 months ago

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma [IMmotion151]

This multi-center, randomized, open-label study will evaluate the efficacy and safety of atezolizumab (MPDL3280A) plus bevacizumab versus sunitinib in participants with inoperable, locally advanced, or metastatic renal cell carcinoma (RCC)...

Added 11 months ago

Prospective Observational Analysis Of CR With Sunitinib Treatment In mRCC Patients (APERÇU)

This prospective study will investigate the characteristics of mRCC patients at time of CR in comparison with mRCC patients non on CR treated with Sunitinib...

Added 6 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.