Latest news articles

Added 1 month ago Drug news

Sutent improves survival in renal cell carcimoma patients who can avoid surgery. Pfizer.

Data from the Phase III CARMENA trial evaluating Sutent (sunitinib) from Pfizer Inc. showed that patients with renal cell carcinoma...

Added 1 month ago Drug news

CHECKMATE 214 trial success for Opdivo + Yervoy (low dose) v. sunitinib for renal cell carcinoma.

Bristol-Myers Squibb Company announced patient-reported outcomes data from the Phase III CheckMate -214 trial in intermediate- and poor-risk patients with...

Added 1 month ago Drug news

EU approves Cabometyx to treat intermediate- or poor- risk advanced renal cell carcinoma.- Ipsen + Exelixis Inc.

Ipsen has announced that the European Commission (EC) has approved Cabometyx (cabozantinib) 20, 40, 60 mg for the first-line treatment...

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Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Fluid Management

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Guidelines

Guidelines on Renal Cell Carcinoma

The European Association of Urology (EAU) Renal Cell Cancer (RCC) Guidelines Panel has compiled these clinical guidelines to provide urologists with evidence-based information and recommendations for the management of renal cell cancer.

Added 2 years ago

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Kidney cancer accounts for 5% and 3% of all adult malignancies in men and women, respectively, thus representing the 7th most common cancer in men and the 10th most common cancer in women.

Added 4 years ago

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Journal articles

Management of Adverse Events Associated with Cabozantinib Therapy in Renal Cell Carcinoma.

This review aims to provide appropriate guidance that will minimize the impact of adverse events and help to maximize the utility of this agent in patients with advanced renal cell carcinoma.

Added 26 days ago

Efficacy of tivozanib treatment after sorafenib in patients with advanced renal cell carcinoma: crossover of a phase 3 study.

Background: Tivozanib is a selective inhibitor of vascular endothelial growth factor receptors 1, 2 and 3 tyrosine kinases. This open-label, crossover clinical study (AV-951-09-902) provided access to tivozanib for patients...

Added 3 months ago

Tivozanib: a new treatment option for renal cell carcinoma.

Tivozanib is a tyrosine kinase inhibitor that targets all vascular endothelial growth factor receptors (VEGFRs), causing inhibition of angiogenesis. It has recently been approved by the European Medicines Agency (EMA)...

Added 3 months ago

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Clinical trials

Cabozantinib Versus Sunitinib for Metastatic Variant Histology Renal Cell Carcinoma

The goal of this clinical research study is to compare the safety and effectiveness of cabozantinib and sunitinib when given to patients with metastatic (has spread) variant histology renal cell carcinoma (vhRCC), a type of kidney cancer.

Added 4 days ago

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma [IMmotion151]

This multi-center, randomized, open-label study will evaluate the efficacy and safety of atezolizumab (MPDL3280A) plus bevacizumab versus sunitinib in participants with inoperable, locally advanced, or metastatic renal cell carcinoma (RCC)...

Added 7 months ago

Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214)

The purpose of this study is to compare the objective response rate, progression free survival and the overall survival of Nivolumab combined with Ipilimumab to Sunitinib monotherapy in patients with previously untreated Renal Cell Cancer.

Added 4 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.