Latest news articles

Added 1 day ago Drug news

Imfinzi + tremelimumab combination does not meet overall survival endpoint in Phase III EAGLE trial for head & neck cancer-AstraZeneca

AstraZeneca and MedImmune, its global biologics research and development arm, announced overall survival (OS) results for the Phase III EAGLE...

Added 4 months ago Drug news

Phase III KEYNOTE-048 trial of Keytruda meets primary endpoint in head and neck squamous cell carcinoma.- Merck Inc.

Merck Inc announced that the pivotal Phase III KEYNOTE-048 trial investigating Keytruda (pembrolizumab) for first-line treatment of recurrent or metastatic...

Added 7 months ago Drug news

Two year overall survival data from CHECKMATE 141 trial of Opdivo for treatment of head and neck cancer.- BMS

Bristol-Myers Squibb Company announced two-year overall survival (OS) data from CheckMate -141, a Phase III open-label, randomized trial evaluating Opdivo...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cushing's Syndrome

Cushing's Syndrome

Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?

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Migraine Knowledge Centre

Migraine Knowledge Centre

The Migraine Knowledge Centre features latest research on the prevalence and impact of migraine, the proposed neurological basis of the condition (and how this is being translated into new and exciting drug therapies), as well as current patient care strategies collated from headache organisations worldwide.

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Guidelines

Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over

This guideline covers assessing and managing cancers of the upper aerodigestive tract in young people (aged 16 and over) and adults. It aims to reduce variation in practice and improve survival.

Added 2 years ago

Nasopharyngeal cancer: EHNS – ESMO – ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best standards of cancer care, based on the findings of evidence-based medicine.

Added 6 years ago

Squamous cell carcinoma of the head and neck: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of recommendations for the best standards of cancer care, based on the findings of evidence-based medicine.

Added 8 years ago

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Journal articles

Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab.

In 2016 and 2017, monoclonal antibodies targeting PD-L1, including atezolizumab, durvalumab, and avelumab, were approved by the FDA for the treatment of multiple advanced cancers. And many other anti-PD-L1 antibodies are under clinical trials.

Added 1 year ago

Immunotherapy for nasopharyngeal cancer-a review.

Nasopharyngeal carcinoma (NPC) is associated with the Epstein-Barr virus (EBV) and characterized by peritumoral immune infiltrate.

Added 1 year ago

Inhaled corticosteroid use and risks of lung cancer and laryngeal cancer

Background:Chronic inflammation has been implicated in the pathogenesis of several cancers, including lung and laryngeal cancer. The objective of the...

Added 5 years ago

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Clinical trials

A Study of Pembrolizumab (MK-3475) for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck (MK-3475-048/KEYNOTE-048)

The primary study hypothesis is that pembrolizumab or pembrolizumab in combination with chemotherapy prolongs progression free survival and overall survival compared to standard treatment.

Added 3 months ago

Observational Study on Biomarkers in Head and Neck Cancer (HNprädBio)

The aim of this clinical research project is to validate the prognostic impact of potential biomarkers on loco-regional control of locally advanced head and neck cancer after definitive or adjuvant radiochemotherapy.

Added 5 years ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Mouth cancer: recognising it and referring early

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Union of European Medical Specialists (via European Accreditation Council for CME)
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