Latest news articles

Added 8 days ago Drug news

Updated results from BEACON CRC trial of Braftovi + Mektovi + cetuximab for patients with BRAFV600E-mutant metastatic colorectal cancer.-Array Biopharma.

As presented at the ESMO 20th World Congress on Gastrointestinal Cancer in June 2018 , the results from the safety...

Added 27 days ago Drug news

Phase III MORA trial of Plenvu in bowel preparation published in Endoscopy.- Norgine.

Norgine announced that results from the Plenvu (polyethylene glycol based bowel preparation) Phase III MORA trial were published in ENDOSCOPY,...

Added 1 month ago Drug news

FDA provides accelerated approval for Yervoy + Opdivo combination to treat microsatellite instability high or mismatch repair deficient metastatic colorectal cancer.

Bristol-Myers Squibb Company announced Opdivo (nivolumab) 3 mg/kg plus low-dose Yervoy (ipilimumab) 1 mg/kg (injections for intravenous use) received approval...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

Diagnosis and management of colorectal cancer

This guideline covers diagnosis and treatment of colorectal cancer. It summarises the evidence and, where appropriate, provides evidence-based recommendations...

Added 6 years ago

Colorectal cancer: diagnosis and management

This guideline covers diagnosing and managing colorectal (bowel) cancer in people aged 18 and over.

Added 6 years ago

Clinical indications for computed tomographic colonography: European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline

This is an official guideline of the European Society of Gastrointestinal Endoscopy (ESGE) and the European Society of Gastrointestinal and Abdominal Radiology (ESGAR). It addresses the clinical indications for the use of...

Added 3 years ago

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Journal articles

Regorafenib: A Review in Metastatic Colorectal Cancer.

Regorafenib (Stivarga®) is an oral small-molecule multiple kinase inhibitor. It is indicated worldwide for patients with metastatic colorectal cancer (mCRC).

Added 14 days ago

Regorafenib therapy in metastatic colorectal cancer patients: markers and outcome in an actual clinical setting.

The oral multikinase inhibitor regorafenib had beneficial effects in randomized clinical phase III trials compared to the placebo in patients with metastatic colorectal cancer (mCRC) who progressed on standard therapies.

Added 14 days ago

Colon cleansing efficacy and safety with 1 L NER1006 versus 2 L polyethylene glycol + ascorbate: a randomized phase 3 trial.

Background: Polyethylene glycol (PEG)-based bowel preparations are effective cleansers but many require high-volume intake. This phase 3, randomized, blinded, multicenter, parallel-group, central reader-assessed study...

Added 23 days ago

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Clinical trials

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 9 months ago

Laparoscopic Surgery for T4 Tumor of the Colon Cancer (LST4C Trial)

The purpose of this study is to compare the short- and long-term survival of laparoscopic surgery and conventional open surgery for T4 colon cancer.

Added 9 months ago

Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer (BEACON CRC)

This is a multicenter, randomized, open-label, 3-arm Phase 3 study to evaluate encorafenib + cetuximab plus or minus binimetinib versus Investigator's choice of either irinotecan/cetuximab or FOLFIRI/cetuximab...

Added 1 month ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Association of adherence to lifestyle recommendations and risk of colorectal cancer: a prospective Danish cohort study

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
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90
Search all CME for Cancer of colon