Cancer of breast

Breast cancer is the second most commonly diagnosed cancer worldwide, behind only lung cancers; this is even more remarkable when its relative rarity in males is noted (males

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Latest news articles

Added 2 days ago Drug news

NICE does not recommend Perjeta + Herceptin combination to treat HER2-positive early breast cancer. Roche.

The National Institute for Health and Care Excellence (NICE) released draft guidance recommending against NHS use of combination Perjeta and...

Added 10 days ago Drug news

FDA accepts NDA for talazoparib for patients with germline (inherited) BRCA-mutated, HER2-negative locally advanced or metastatic breast cancer.- Pfizer.

Pfizer Inc. announced the FDA accepted for filing and granted Priority Review designation to the company's New Drug Application for...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Communicating Metastatic Breast Cancer Learning Zone

Communicating Metastatic Breast Cancer Learning Zone

This learning zone offers a short overview of the challenges faced by both healthcare professionals and patient when communicating end-stage or metastatic cancer.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Advanced breast cancer: diagnosis and treatment

This guideline covers care and support for people with advanced (stage 4) breast cancer.

Added 9 years ago

3rd ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 3)

The ESO-ESMO 3rd international consensus guidelines for advanced breast cancer (ABC3) focus on methodology, assessment guidelines and treatment recommendations for specific breast cancer subtypes...

Added 2 months ago

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The updated ESMO Clinical Practice Guidelines provide information on the current management of primary breast cancer, including screening, diagnosis and...

Added 2 years ago

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Journal articles

Synergistic antitumor activity by combining trastuzumab with retinoic acid in HER2 positive human breast cancer cells.

Breast cancer can be classified into molecular subtypes. Tumors overexpressing HER2 protein are more aggressive and metastatic; hence, patients have a poor prognosis.

Added 2 days ago

Trastuzumab-induced cardiotoxicity and its risk factors in real-world setting of breast cancer patients.

The aim of this retrospective study was to determine the frequency and timing of trastuzumab cardiotoxicity and its risk factors in real-world setting.

Added 2 days ago

A Review of Fulvestrant in Breast Cancer.

Fulvestrant is a selective estrogen receptor degrader that binds, blocks and degrades the estrogen receptor (ER), leading to complete inhibition of estrogen signaling through the ER. This review article further explains the mechanism of action...

Added 4 months ago

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Clinical trials

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer (EarLEE-2)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 7 months ago

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer (EarLEE-1)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 7 months ago

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. (OlympiAD)

This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice of capecitabine, vinorelbine or eribulin in...

Added 7 months ago

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Blog Posts

Alex Keen

ELCC 2018 ‒ Roundup of this year’s conference

Posted 2 months ago

At the recent ELCC, held from 11‒14 April 2018, several hundred abstracts were presented detailing the latest cutting-edge research in lung cancer treatment and care. Brief summaries of some of the key abstracts are found here.

Alex Keen

ELCC 2018 ‒ And the Heine H. Hansen Award goes to…

Posted 2 months ago

Discover this year's Heine H. Hansen award winner, given to a scientific investigator who has made special, wide-reaching and significant contributions to lung cancer research and education, recognising their lifelong achievements.

Alex Keen

EBCC 2018 – Roundup of this year's conference

Posted 2 months ago

At the recent European Breast Cancer Conference the best and brightest in breast cancer research and care met to present and discuss the latest breakthroughs. Brief summaries of some of the key abstracts are found here.

CME

Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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