Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Cancer of breast

Breast cancer is the second most commonly diagnosed cancer worldwide, behind only lung cancers; this is even more remarkable when its relative rarity in males is noted (males

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Latest news articles

Added 1 day ago Drug news

CHMP recommends Ontruzant (trastuzumab biosimilar) to treat breast cancer and gastric cancer. Samsung Bioepis + Merck Inc.

Samsung Bioepis Co., Ltd. announced that the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has...

Added 6 days ago Drug news

MONARCH 3 study positive for abemaciclib in combination with a nonsteroidal aromatase inhibitor as treatment of postmenopausal women with advanced breast cancer.- Eli Lilly.

MONARCH 3 is a global Phase III, double-blind, placebo-controlled study, which evaluated the efficacy and safety of abemaciclib in combination...

Added 8 days ago Drug news

Phase III REFLECTIONS B327-02 study of PF-05280014 (trastuzumab biosimilar) met primary objective in HER2-positive metastatic breast cancer.- Pfizer.

Pfizer announced positive findings from REFLECTIONS B327-02 (n=707), a pivotal Phase III randomized, double-blind comparative safety and efficacy study of...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Breakthrough Cancer Pain Learning Zone

Invitation to watch the online broadcast of the BeCOn OWN event 'Shifting paradigms in BTcP management' on June 16 2017.

Visit Breakthrough Cancer Pain Learning Zone

Bedwetting

Essential screening, diagnosis and best strategies to manage bedwetting.

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Guidelines

Breast screening: clinical guidelines for screening assessment

The aim of assessment is to obtain a definitive and timely diagnosis of all potential abnormalities detected during screening.

Added 4 months ago

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

The updated ESMO Clinical Practice Guidelines provide information on the current management of primary breast cancer, including screening, diagnosis and...

Added 2 years ago

Preventing excess weight gain

This guideline makes recommendations on behaviours that may help people maintain a healthy weight or prevent excess weight gain. The...

Added 2 years ago

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Journal articles

Ribociclib for post-menopausal women with HR+/HER2- advanced or metastatic breast cancer.

Introduction: The introduction of CDK4/6 inhibitors, such as ribociclib, has changed the treatment landscape for post-menopausal women with HR+/HER2- advanced or metastatic breast cancer.

Added 6 days ago

Ribociclib: First Global Approval.

Ribociclib is an oral, small-molecule inhibitor of cyclin-dependent kinase (CDK) 4 and 6 that is under development by Novartis for the treatment of cancer.

Added 6 days ago

Ribociclib for the treatment of advanced hormone receptor-positive, HER2-negative breast cancer.

CDK4/6 inhibitors are a promising new class of drugs for hormone-receptor-positive breast cancer and have been shown to overcome and delay hormone resistance in advanced breast cancer.

Added 6 days ago

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Clinical trials

A Study of Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer (MONARCH 3)

The main purpose of this study is to evaluate how effective nonsteroidal aromatase inhibitors (NSAI) plus abemaciclib are in postmenopausal women with breast cancer.

Added 3 years ago

A Study Of PF-05280014 [Trastuzumab-Pfizer] Or Herceptin® [Trastuzumab-EU] Plus Paclitaxel In HER2 Positive First Line Metastatic Breast Cancer Treatment (REFLECTIONS B327-02)

The current study will compare the efficacy, safety, pharmacokinetics and immunogenicity of PF-05280014 in combination with paclitaxel versus trastuzumab sourced from the European Union (trastuzumab-EU)...

Added 4 days ago

Study of Efficacy and Safety of LEE011 in Postmenopausal Women With Advanced Breast Cancer.(MONALEESA-2)

This is a multi-center, randomized, double-blinded, placebo controlled trial.

Added 4 years ago

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Blog Posts

Fiona Holland

What to say and do when someone has cancer

Posted 7 months ago

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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