Cancer of breast

Breast cancer is the second most commonly diagnosed cancer worldwide, behind only lung cancers; this is even more remarkable when its relative rarity in males is noted (males

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Latest news articles

Added 1 day ago Drug news

Complete response letter for trastuzumab biosimilar.- Pfizer

Pfizer Inc.announced that it received a Complete Response Letter (CRL) from the FDA in response to the Biologics License Application...

Added 7 days ago Drug news

Glembatumumab vedotin fails Phase II trial for triple negative breast cancer.- Celldex Therapeutics.

Celldex Therapeutics, Inc. reported that the Company's randomized, Phase IIb METRIC Study of glembatumumab vedotin compared to Xeloda (capecitabine) in...

Added 8 days ago Drug news

Phase III OlympiAD trial overall survival results for Lynparza in metastatic breast cancer.- AstraZeneca + Merck Inc.

AstraZeneca and Merck presented data from the Phase III OlympiAD trial showing the final overall survival (OS) results for Lynparza...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Communicating Metastatic Breast Cancer Learning Zone

Communicating Metastatic Breast Cancer Learning Zone

This learning zone offers a short overview of the challenges faced by both healthcare professionals and patient when communicating end-stage or metastatic cancer.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

3rd ESO–ESMO International Consensus Guidelines for Advanced Breast Cancer (ABC 3)

The ESO-ESMO 3rd international consensus guidelines for advanced breast cancer (ABC3) focus on methodology, assessment guidelines and treatment recommendations for specific breast cancer subtypes...

Added 14 days ago

Breast screening: clinical guidelines for screening assessment

The aim of assessment is to obtain a definitive and timely diagnosis of all potential abnormalities detected during screening.

Added 11 months ago

Preventing excess weight gain

This guideline makes recommendations on behaviours that may help people maintain a healthy weight or prevent excess weight gain. The...

Added 3 years ago

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Journal articles

A Review of Fulvestrant in Breast Cancer.

Fulvestrant is a selective estrogen receptor degrader that binds, blocks and degrades the estrogen receptor (ER), leading to complete inhibition of estrogen signaling through the ER. This review article further explains the mechanism of action...

Added 2 months ago

Fulvestrant 500 milligrams as endocrine therapy for endocrine sensitive advanced breast cancer patients in the real world: the Ful500 prospective observational trial.

The observational prospective trial herein presented aimed at evaluating the efficacy of fulvestrant 500 mg in the treatment of endocrine sensitive advanced breast cancer patients from the real world setting.

Added 2 months ago

Efficacy of fulvestrant in the treatment of postmenopausal women with endocrine-resistant advanced breast cancer in routine clinical practice.

This study aimed to describe the efficacy of fulvestrant 500 mg in postmenopausal women with estrogen receptor (ER)-positive advanced/metastatic breast cancer who had disease progression after receiving anti-estrogen therapy in clinical practice...

Added 2 months ago

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Clinical trials

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer (EarLEE-2)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 5 months ago

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer (EarLEE-1)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 5 months ago

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. (OlympiAD)

This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice of capecitabine, vinorelbine or eribulin in...

Added 5 months ago

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Blog Posts

Alex Keen

ELCC 2018 ‒ Roundup of this year’s conference

Posted 7 days ago

At the recent ELCC, held from 11‒14 April 2018, several hundred abstracts were presented detailing the latest cutting-edge research in lung cancer treatment and care. Brief summaries of some of the key abstracts are found here.

Alex Keen

ELCC 2018 ‒ And the Heine H. Hansen Award goes to…

Posted 21 days ago

Discover this year's Heine H. Hansen award winner, given to a scientific investigator who has made special, wide-reaching and significant contributions to lung cancer research and education, recognising their lifelong achievements.

Alex Keen

EBCC 2018 – Roundup of this year's conference

Posted 28 days ago

At the recent European Breast Cancer Conference the best and brightest in breast cancer research and care met to present and discuss the latest breakthroughs. Brief summaries of some of the key abstracts are found here.

CME

Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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