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Added 9 hours ago Drug news

JNJ 42756493 filed with the FDA for metastatic urothelial cancer.- Janssen R&D.

Janssen Pharmaceutical announced that a New Drug Application (NDA) has been submitted to the FDA seeking approval of JNJ 42756493...

Added 2 months ago Drug news

FDA restrictions on Keytruda and on Tecentriq for bladder cancer.

The FDA has restricted use of Keytruda (pembrolizumab) from Merck Inc.and Tecentriq (atezolizumab) from Roche among patients with locally advanced...

Added 3 months ago Drug news

EMA warning relating to use of Keytruda and Tecentriq in bladder cancer. Merck Inc. and Roche .

Early data from two clinical trials ( Keynote-361 and IMvigor130 ) show reduced survival with Keytruda (pembrolizumab) and Tecentriq (atezolizumab)...

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Guidelines

Guidelines on Upper Urinary Tract Urothelial Cell Carcinomas

The European Association of Urology (EAU) Non-muscle-invasive Bladder Cancer (NMIBC) Guidelines Panel has compiled these clinical guidelines to provide urologists...

Added 2 years ago

Guidelines on Non-muscle-invasive Bladder Cancer (Ta, T1 and CIS)

This overview represents the updated European Association of Urology (EAU) Guidelines for Non-muscle-invasive Bladder Cancer (NMIBC), TaT1 and carcinoma in situ (CIS). The information presented is limited to urothelial carcinoma...

Added 2 years ago

Guidelines on Muscle-invasive and Metastatic Bladder Cancer

The European Association of Urology (EAU) Guidelines Panel for Muscle-invasive and Metastatic Bladder Cancer (MIBC) have prepared these guidelines to help urologists assess the evidence-based management of MIBC...

Added 2 years ago

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Journal articles

Diagnostic accuracy of C-11 choline and C-11 acetate for lymph node staging in patients with bladder cancer: a systematic review and meta-analysis.

We aimed to assess the diagnostic accuracy of C-11 choline and C-11 acetate positron emission tomography/computed tomography (PET/CT) for lymph node (LN) staging in bladder cancer (BC) patients through a systematic review...

Added 8 months ago

The anti-PD-1 era - an opportunity to enhance radiotherapy for patients with bladder cancer.

An urgent need exists to improve the outcomes of patients with muscle-invasive bladder cancer (MIBC), and especially of those with metastatic disease. Treatments that enhance antitumour immune responses...

Added 8 months ago

Immunotherapy in metastatic urothelial carcinoma: focus on immune checkpoint inhibition.

Immunotherapy has been used in localized urothelial carcinoma for decades, especially in the treatment of superficial disease, in which instillation of BCG is a commonly used treatment option.

Added 8 months ago

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Clinical trials

Study of Pembrolizumab With or Without Platinum-based Combination Chemotherapy Versus Chemotherapy Alone in Urothelial Carcinoma (MK-3475-361/KEYNOTE-361)

The purpose of this study is to determine the efficacy and safety of pembrolizumab (MK-3475) with or without chemotherapy versus chemotherapy alone in participants with advanced or metastatic urothelial carcinoma (bladder cancer).

Added 2 months ago

Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma (IMvigor130)

A Phase III, randomised study of atezolizumab alone and in combination with chemotherapy versus chemotherapy alone in participants with untreated advanced urothelial cancer.

Added 2 months ago

Vicinium Treatment for Subjects With Non-muscle Invasive Bladder Cancer Previously Treated With BCG

Because of the high risk for development of muscle invasive disease, cystectomy is recommended for CIS, high-grade Ta and T1 patients who experience disease recurrence following intravesical therapy. Vicinium is an experimental agent...

Added 2 months ago

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Fiona Holland

Fiona worked in the fitness and wellness industry in the US for 13 years, supporting behaviour change in a variety of settings. Fiona’s research interests lie broadly within health and wellbeing. She is particularly interested in qualitative methodologies in the areas of body image ... Read more

What to say and do when someone has cancer

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

CME

Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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