Latest news articles

Added 1 year ago Drug news

BD issues statement on FDA relating to paclitaxel-coated devices and long term mortality

BD (Becton, Dickinson and Company) issued the following statement related to the recent letter from FDA to health care providers...

Added 1 year ago Drug news

Positive trial data for Lutonix 014 Drug-Coated Balloon to treat narrowed or obstructed arteries below the knee. Becton Dickinson

BD (Becton, Dickinson and Company) announced the safety and efficacy data from the Lutonix Drug-Coated Balloon (DCB) IDE, level 1...

Added 2 years ago Drug news

REX 001 enters Phase III trials as a treatment for critical limb ischaemia.- Rexgenero Ltd.

Rexgenero Ltd, a clinical-stage regenerative medicine company developing advanced cell-based therapies with a focus on Critical Limb Ischemia (CLI), announces...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.



See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

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2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)

In this document, the term ‘peripheral arterial diseases’ encompasses all arterial diseases other than coronary arteries and the aorta. This should be clearly distinguished from the term ‘peripheral artery disease’...

Added 2 years ago

Peripheral arterial disease: diagnosis and management

This guideline covers diagnosing and managing peripheral arterial disease (PAD) in people aged 18 and over.

Added 7 years ago

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Journal articles

Edoxaban in Atrial Fibrillation and Venous Thromboembolism-Ten Key Questions and Answers: A Practical Guide.

Edoxaban is the fourth non-vitamin K antagonist oral anticoagulant now available for clinical use in the prevention of stroke/systemic embolism in atrial fibrillation (AF) and in the treatment of venous thromboembolism (VTE) ...

Added 2 years ago

Edoxaban: A direct oral anticoagulant.

Purpose: The pharmacology, pharmacokinetics, pharmacodynamics, clinical efficacy, safety, and place in therapy of edoxaban for prevention of stroke in patients with nonvalvular atrial fibrillation (AF) and ...

Added 2 years ago

Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF-TIMI48 Trial.

Background: We studied the concomitant use of single antiplatelet therapy (SAPT) on the efficacy and safety of the anti-Xa agent...

Added 4 years ago

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