Latest news articles

Added 5 months ago Drug news

Endologix receives IDE approval for a pivotal trial for the Nellix Chimney EndoVascular Aneurysm Sealing Protocol

- Endologix, Inc. a developer and marketer of innovative treatments for aortic disorders, announced that it has received Investigational Device...

Added 1 year ago Drug news

FDA Advisory Committee recommends premarket approval for Incraft AAA Stent Graft System for infrarenal abdominal aortic aneurysms. - Cordis/Cardinal Health.

Cardinal Health announced that the FDA Circulatory System Devices Panel of the Medical Devices Advisory Committee has provided a favorable...

Added 2 years ago Drug news

FORWARD IDE trial shows benefits of Nellix EVAS System in reduced leakage and mortality in patients with abdominal aortic aneurysms- Endologix

Endologix announced the presentation of two-year clinical data from the Company's Nellix EVAS FORWARD IDE trial that prospectively enrolled patients...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.



See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

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A practical guideline for the haematological management of major haemorrhage

The aim of these updated guidelines is to provide recommendations for the haematological management of major haemorrhage in any clinical situation...

Added 4 years ago

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases

Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult.

Added 5 years ago

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Journal articles

Fibrinogen concentrate administration attributes to significant reductions of blood loss and transfusion requirements in thoracic aneurysm repair.

Background: Repair of thoracic aortic aneurysm (TAA) is often associated with massive hemorrhage aggravated by dilutional coagulopathy with severe hypofibrinogenemia. Although only fresh frozen plasma (FFP) is available for...

Added 1 month ago

Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial.

Objectives: We assessed whether fibrinogen concentrate as targeted first-line hemostatic therapy was more effective than placebo or a standardized transfusion algorithm in controlling coagulopathic bleeding in patients undergoing...

Added 1 month ago

The relationship between fibrinogen and in-hospital mortality in patients with type A acute aortic dissection.

Background and purpose: Fibrinogen plays an important role in hemostasis and thrombosis and is proven to have prognostic significance in patients with cardiovascular disease. We examined the utility of fibrinogen as a prognostic...

Added 8 months ago

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