Latest news articles

Added 1 month ago Drug news

Biogen plans regulatory filing at FDA for aducanumab in Alzheimer's disease based on new phase III analyses.

Biogen announced that, after consulting with the FDA, Biogen plans to pursue regulatory approval for aducanumab, an investigational treatment for...

Added 2 months ago Drug news

Phase III trials of E 2609 for Alzheimers will be discontinued

Eisai Co and Biogen announced the decision to discontinue the Phase III clinical studies (MISSION AD1, AD2) on the investigational...

Added 5 months ago Drug news

Amgen, Novartis And Banner Alzheimer's Institute discontinue clinical research program With CNP 520 For Alzheimer's Prevention

Amgen, Novartis and Banner Alzheimer's Institute announced the collective decision to discontinue investigation of the BACE1 inhibitor CNP 520 (umibecestat)...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Delirium: prevention, diagnosis and management

This guideline covers diagnosing and treating delirium in people aged 18 and over in hospital and in long-term residential care or a nursing home. It also covers identifying people at risk of developing delirium in these settings and...

Added 3 months ago

Risk reduction and management of delirium

This guideline provides recommendations based on current evidence for best practice in the detection, assessment, treatment and follow up of adults with delirium, as well as reducing the risk of delirium.

Added 3 months ago

Dementia: assessment, management and support for people living with dementia and their carers

This guideline covers diagnosing and managing dementia (including Alzheimer’s disease). It aims to improve care by making recommendations on training staff and helping carers to support people living with dementia.

Added 3 months ago

Search all guidelines for Alzheimer's disease and dementia
 

Journal articles

A Systematic Review of Evidence for a Role of Rest-Activity Rhythms in Dementia.

Background: Rest-activity rhythm (RAR) disruption may be a risk factor for dementia that can be objectively measured with wearable accelerometers. It is possible that risk monitoring and preventive interventions could be developed...

Added 20 days ago

A systematic review of the integration of palliative care in dementia management.

Objective: Dementia is a progressive illness with a complex biopsychosocial constellation of symptoms faced by millions of individuals and families worldwide. Palliative care teams have specialized in symptom management and...

Added 20 days ago

Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial.

Objective: To determine whether 24 months of minocycline treatment can modify cognitive and functional decline in patients with mild AD.

Added 23 days ago

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Clinical trials

Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia With Lewy Bodies (AscenD-LB)

This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, proof-of-principle study of neflamapimod versus matching placebo (randomized 1:1) administered with food for 16 weeks in subjects with DLB.

Added 20 days ago

A Study to Evaluate Safety of Long-term AL001 Dosing in FTD Patients

A Phase 2 open label study evaluating the safety, tolerability, PK and PD of AL001 in participants with a Granulin mutation or C9orf72 mutation causative of frontotemporal dementia.

Added 20 days ago

PTI-125 for Mild-to-moderate Alzheimer's Disease Patients

This is a Phase 2b, Randomized, Double-blind, Placebo-controlled, multiple dose study of PTI-125 in mild-to-moderate Alzheimer's disease patients. A total of sixty (60) patients will be enrolled in the study.

Added 2 months ago

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Dr Cornelia Meisenberg

Dr Conny Meisenberg is a medical writer at EPG Health. She joined EPG Health in 2019 following 7 years of postdoctoral research in the oncology field.

Progressive Supranuclear Palsy (PSP)

What is Progressive Supranuclear Palsy (PSP)? Review the causes, treatment and current trials for this uncommon, degenerative disorder.

CME

Diabetes care, antivirals for flu and dementia risk: update clinical February 2016

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Hallucinations - red flag symptoms

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Alzheimer's disease: clinical review

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Search all CME for Alzheimer's disease and dementia