Latest news articles

Added 1 month ago Drug news

OPTION trial initiated to compare WATCHMAN FLX left atrial appendage closure platform to first-line oral anticoagulants

Boston Scientific Corporation has initiated the OPTION trial to compare safety and effectiveness of the next-generation WATCHMAN FLX left atrial...

Added 2 months ago Drug news

Tenecteplase enters phase III TIMELESS trial to treat acute ischemic stroke

Genentech recently initiated the Phase III TIMELESS trial to evaluate TNKase (tenecteplase) in people with acute ischemic stroke (AIS) when...

Added 4 months ago Drug news

Phase IIIb ELIMINATE-AF study of Lixiana shows safety and efficacy in bleeding events

Daiichi Sankyo announced results from phase IIIb ELIMINATE-AF, a prospective, randomised, open label, blinded endpoint evaluation (PROBE) design study assessing...

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Learning Zones

An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.



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European Stroke Organisation (ESO) guidelines on glycaemia management in acute stroke

Hyperglycaemia is a frequent complication in acute stroke that has been shown to be independently associated with larger infarct size, haematoma growth, poor clinical outcome and mortality.

Added 1 year ago

European Academy of Neurology and European Stroke Organization consensus statement and practical guidance for pre-hospital management of stroke

The objective is to recommend evidence-based practices for the management of patients with suspected stroke in the pre-hospital setting.

Added 1 year ago

Management of Atherosclerotic Carotid and Vertebral Artery Disease: 2017 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)

The European Society for Vascular Surgery (ESVS) has prepared guidelines for treating patients with atherosclerotic carotid and vertebral artery (VA) disease.

Added 1 year ago

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Journal articles

Dementia: new vistas and opportunities.

Over the past four decades, Alzheimer disease has become near synonymous with dementia and the amyloid/tau hypothesis as its dominant explanation. However, this monorail approach to etiology has failed to yield a single...

Added 1 month ago

Migraine and cardiovascular disease: systematic review and meta-analysis.

Objective: To evaluate the association between migraine and cardiovascular disease, including stroke, myocardial infarction, and death due to cardiovascular disease.

Added 3 months ago

Migraine headache and ischemic stroke risk: an updated meta-analysis.

Background: Observational studies, including recent large cohort studies which were unavailable for prior meta-analysis, have suggested an association between migraine headache and ischemic stroke. We performed an updated...

Added 3 months ago

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Clinical trials

Trial of Andexanet in ICH Patients Receiving an Oral FXa Inhibitor

Randomized, controlled clinical trial evaluating the efficacy and safety of andexanet versus usual standard of care in patients with intracranial hemorrhage anticoagulated with a direct oral anticoagulant

Added 1 month ago

A Study in Patients With Acute Major Bleeding to Evaluate the Ability of Andexanet Alfa to Reverse the Anticoagulation Effect of Direct and Indirect Oral Anticoagulants (Extension Study)

The purpose of this study is to evaluate the hemostatic efficacy of andexanet alfa in patients receiving a factor Xa inhibitor who are experiencing an acute major bleed. The safety of andexanet will also be studied.

Added 4 months ago

Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo (DAWN)

The purpose of the study is to evaluate the hypothesis that Trevo thrombectomy plus medical management leads to superior clinical outcomes at 90 days as compared to medical management alone in appropriately selected subjects...

Added 1 year ago

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Stroke: clinical review

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MIMS Learning - Monthly Index of Medical Specialities
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Search all CME for Acute cerebrovascular disease