Data from multiple sources - Curated by Marshall Pearce - Last updated 06 June 2017

Latest news articles

Added 7 days ago Drug news

Trial analysis presented at the American Heart Association (AHA) shows Lixiana has greater reductions in ischaemic events compared to warfarin

Sub analysis of ENGAGE AF-TIMI 48 trial showed Lixiana has greater reductions in ischaemic events compared to warfarin.

Added 9 days ago Drug news

DAWN trial data published: Compelling evidence in treating late window & wake-up stroke patients

The New England Journal of Medicine published the results of the DAWN Trial of Trevo Retriever in stroke.


Added 20 days ago Drug news

Five-year data from PREVAIL study of Watchman LAAC shows safety and effectiveness in stroke risk reduction.- Boston Scientific.

Boston Scientific announced final five-year outcomes data from the PREVAIL study of the Watchman Left Atrial Appendage Closure (LAAC) Device....

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An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.



Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Guideline for reversal of antithrombotics in intracranial hemorrhage.

The use of antithrombotic agents, including anticoagulants, antiplatelet agents, and thrombolytics has increased over the last decade and is expected to continue to rise.

Added 8 months ago

European Stroke Organisation (ESO) guidelines for the management of temperature in patients with acute ischemic stroke

Hyperthermia is a frequent complication in up to 50% of patients with acute ischemic stroke, and it was shown to...

Added 2 years ago

European Stroke Organisation (ESO) guidelines for the management of spontaneous intracerebral hemorrhage

These guidelines inform the management of Intracerebral hemorrhage (ICH) based on evidence for the effects of treatments in randomized controlled...

Added 3 years ago

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Journal articles

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.

The effect of endovascular thrombectomy that is performed more than 6 hours after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is disproportionately severe relative to the infarct volume...

Added 9 days ago

Anticoagulation-associated intracranial haemorrhage in the era of reversal agents

In patients taking oral anticoagulants (OACs), the annual rate of intracranial hemorrhage is 0.3% to 0.6%. Of these bleeds, 46% to 86% are intracerebral; 13% to 45% are subdural, and 1% to 8% are subarachnoidal. 

Added 1 month ago

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease.

Background: We evaluated whether rivaroxaban alone or in combination with aspirin would be more effective than aspirin alone for secondary cardiovascular prevention.

Added 1 month ago

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Clinical trials

Clinical Mismatch in the Triage of Wake Up and Late Presenting Strokes Undergoing Neurointervention With Trevo (DAWN)

The purpose of the study is to evaluate the hypothesis that Trevo thrombectomy plus medical management leads to superior clinical outcomes at 90 days as compared to medical management alone in appropriately selected subjects...

Added 9 days ago

Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease (COMPASS)

The primary purpose of this study is to evaluate whether treatment with rivaroxaban and aspirin or rivaroxaban alone is better than aspirin alone in prevention of heart attacks, stroke or cardiovascular death...

Added 5 years ago

An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome

The purpose of this study is to determine whether rivaroxaban in addition to standard care reduces the risk of the composite of cardiovascular death, myocardial infarction, or stroke in patients...

Added 1 month ago

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Stroke: clinical review

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MIMS Learning - Monthly Index of Medical Specialities
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