WELCOME to epgonline.org

Access trusted, independent sources of clinical content for the United Kingdom as well as other regions. Registration is quick and simple, providing you with unlimited access to all content and features.
 

Latest News

Added 1 day ago Drug news

FDA approves BRUKER MALDI Biotyper CA system for the identification of C. auris which can cause serious infections in hospitalized patients.-Bruker Daltonik GmbH.

The FDA has authorized the first test to identify the emerging pathogen Candida auris (C. auris), which can cause serious...

Added 1 minutes ago Drug news

Basilea licenses ARQ 087 from ArQule Inc for non Chinese markets as a treatment for biliary cancer.

Basilea Pharmaceutica Ltd. announced that it has entered into a license agreement with ArQule, Inc. for its oncology drug candidate...

Added 1 minutes ago Drug news

Higher cleansing scores correlate with increased polyp detection in patients with potential colorectal cancer- Norgine B.V.

Norgine B.V. announced new data showing that there is a strong correlation between higher cleansing scores and increased polyp detection...

Looking to the horizon - Breakthrough drugs and treatments

Marshall Pearce

Antibody-drug conjugates (ADCs)

Posted 1 year ago

Over the past couple of decades, there have been advances in a class of drugs which for a long time was purely theoretical: antibody-drug conjugates (ADCs). The concept underlying ADCs is elegant – what if it were possible to ‘target’ particular groups of cells with a cytotoxic agent, rather than exposing every cell of the body to it?

Marshall Pearce

Cancer immunotherapies

Posted 1 year ago

It was the winner of the 1908 Nobel prize for medicine, Paul Ehrlich, who is first credited with discussing the concept of a “magic bullet”, able to target specific cells without damaging healthy tissue. With the advent of immunotherapy, as well as antibody-drug conjugates, we are beginning to realise this vision.

Marshall Pearce

How close are we to a disease-modifying treatment for Alzheimer’s?

Posted 4 months ago

Alzheimer’s disease is a snowballing problem, one that is currently without a convincing solution. The progressive decline in cognitive function seen in patients with Alzheimer’s disease is associated strongly with plaques formed of amyloid beta in the brain, creating neurofibrillary tangles and leading to neuronal destruction. While some treatments improve cognition in the short-term, current therapeutic options are unable to modify or slow the disease process.