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Latest News

Added 4 hours ago Drug news

FDA expands Revlimid (lenalidomide) indication to include use for patients with multiple myeloma as maintenance therapy following autologous hematopoietic stem cell transplant.-Celgene

Celgene Corporation announced that the FDA has expanded the existing indication for Revlimid (lenalidomide) 10 mg capsules to include use...

Added 1 day ago Drug news

FDA accepts resubmission (NDA) of Dextenza (dexamethasone insert) 0.4 mg for intracanalicular use, for the treatment of ocular pain occurring after ophthalmic surgery.-Ocular Therapeutix, Inc.

Ocular Therapeutix, Inc. announced that the Company’s New Drug Application (NDA) resubmission for Dextenza (dexamethasone insert) 0.4 mg for intracanalicular...

Added 1 day ago Drug news

EU approves change to authorisation for Repatha (evolocumab) to approve single-dose delivery option in dyslipidaemia treatment- Amgen

Amgen announced that the European Commission (EC) has adopted a decision to change the Repatha (evolocumab) marketing authorization, approving a...

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Latest Journal Abstracts

Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes

The electrophysiological effect of levosimendan, a novel Ca(2+)-sensitizing positive inotropic agent and vasodilator, was examined on rat mesenteric arterial myocytes using the patch clamp technique.

Added 2 hours ago

Management of advanced or refractory heart failure

Advanced heart failure, also be defined as stage D heart failure, characterized by advanced structural heart disease and marked symptoms of heart failure at rest...

Added 3 hours ago

Chronotropy: the Cinderella of heart failure pathophysiology and management

A hallmark characteristic of chronic HF, associated with either a reduced (HFrEF) or preserved ejection fraction (HFpEF), is a markedly reduced capacity for physical exertion.

Added 3 hours ago

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Latest Guidelines

Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015) - short version

In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and Emergency Medicine), twelve German medical societies published...

Added 1 day ago

Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit

To revise the "Clinical Practice Guidelines for the Sustained Use of Sedatives and Analgesics in the Critically Ill Adult" published in Critical Care Medicine in 2002.

Added 1 day ago

Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision.

Allergic rhinitis represents a global health problem affecting 10% to 20% of the population.

Added 1 day ago

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