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Added 20 hours ago Drug news

FDA approves Tavalisse to treat chronic immune thrombocytopenia . Rigel Pharma.

Rigel Pharmaceuticals, Inc. announced that the FDA approved Tavalisse (fostamatinib disodium hexahydrate) for the treatment of thrombocytopenia in adult patients...

Added 20 hours ago Drug news

Study of Zalviso in moderate to severe pain published in Anesthesiology journal.- AcelRx Pharma.

AcelRx Pharmaceuticals announced the publication of an analysis of the pharmacokinetic characteristics of sublingually administered tablets containing Zalviso (sufentanil sublingual...

Added 20 hours ago Drug news

Positive results of LIBERTY Phase IIIb trial of Aimovig in episodic migraine treatmant.-Novartis

Novartis has announced full results from the Phase IIIb LIBERTY trial of Aimovig (erenumab, AMG 334) in episodic migraine patients...

Looking to the horizon - Breakthrough drugs and treatments

Marshall Pearce

Antibody-drug conjugates (ADCs)

Posted 1 year ago

Over the past couple of decades, there have been advances in a class of drugs which for a long time was purely theoretical: antibody-drug conjugates (ADCs). The concept underlying ADCs is elegant – what if it were possible to ‘target’ particular groups of cells with a cytotoxic agent, rather than exposing every cell of the body to it?

Marshall Pearce

Cancer immunotherapies

Posted 11 months ago

It was the winner of the 1908 Nobel prize for medicine, Paul Ehrlich, who is first credited with discussing the concept of a “magic bullet”, able to target specific cells without damaging healthy tissue. With the advent of immunotherapy, as well as antibody-drug conjugates, we are beginning to realise this vision.

Marshall Pearce

How close are we to a disease-modifying treatment for Alzheimer’s?

Posted 4 months ago

Alzheimer’s disease is a snowballing problem, one that is currently without a convincing solution. The progressive decline in cognitive function seen in patients with Alzheimer’s disease is associated strongly with plaques formed of amyloid beta in the brain, creating neurofibrillary tangles and leading to neuronal destruction. While some treatments improve cognition in the short-term, current therapeutic options are unable to modify or slow the disease process.