Post-operative complications of solid organ transplantation can be categorised into three groups:
those arising from recipient comorbidities such as diabetes, obesity, renal insufficiency and cardiovascular disease
secondary complications arising from waiting for an allograft, e.g. musculoskeletal deconditioning, malnutrition, coagulopathy, reduced cardiopulmonary function, immune compromise
complications consequent to surgery (Diaz and O'Connor, 2011).
Ten-year graft survival following solid organ transplantation is shown in the figure below (Collaborative Transplant Study (CTS), 2016). Although short-term survival is excellent (>90%), long-term survival is poor reflecting recurrence of disease, development of chronic rejection or complications related to the need for long-term immunosuppression.