Welcome to the Transplantation Knowledge Centre

Welcome to the Transplantation Knowledge Centre, an online resource intended to educate healthcare professionals in best practice for the transplantation of various organs.

This Knowledge Centre will cover the indications for transplantation, discussing the most common conditions resulting in organ failure; epidemiology, providing global statistics for organ donation and transplantation, the burden of disease and complication rates; the surgical techniques used, supported by current guideline recommendations; the various methods for immunosuppression, such as calcineurin inhibitors, induction therapy and anti-metabolites; long-term outcomes, discussing the causes of mortality and exploring the options for improvement; and finally, future developments, evaluating the use of regenerative medicine and organs grown ex vivo.

In addition, slide presentations from the European Society for Organ Transplantation Congress 2017  discussing the latest clinical trial data for kidney and liver transplantation are available to view and download.

Transplantation Overview

Read about the Indications, Epidemiology and Immunosuppression in solid organ transplantation, the long-term outcomes and complications of transplantation, including future developments on the horizon.

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European Society for Organ Transplantation Congress 2017

View slide presentations discussing the results of clinical trials into kidney and liver transplantation, presented at ESOT 2017.

Indications for Transplantation

Find out more about the key candidate organs for transplantation, from kidney, liver, heart and lung to others such as the pancreas, intestine, cornea and haematopoietic stem cells.

Epidemiology

Read more about the epidemiology of transplantation. How are suitable candidates selected, how many living and deceased donors are there and what are the complication rates?

Surgical Procedures

Learn more about the surgical procedures for transplantation, how they are constantly evolving and what guidelines and studies endorse as best practice.

Immunosuppression

Discover the wide-range of pharmacological immunosuppressive methods available, such as calcineurin inhibitors, mTOR inhibitors, anti-metabolites and biologics, alongside typical treatment regimens.

Long-term Outcomes

Learn why transplantation is now recognised as the best therapy for end-stage organ failure, improving QoL and life expectancy, however, significant morbidities remain which require improvement.

Future Developments

Explore the future developments in organ transplantations, designed to minimise graft failure and improve the availability of organs suitable for transplantation.