In your opinion why was the AUGUSTUS trial such a game changer?

Professor Storey describes how the AUGUSTUS trial answered two very distinct questions:

  • is a NOAC such as apixaban at its licensed dose for atrial fibrillation superior in terms of safety efficacy balance compared to a vitamin K antagonist such as warfarin? 
  • what is the risk and or benefit is of having aspirin in the combination of antithrombotic drugs.
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