Drug news
NICE does not recommend Praluent (alirocumab) to treat high cholesterol-Sanofi
The National Institute for Health and Care Excellence has issued draft guidance not recommending Praluent (alirocumab)from Sanofi,for people with high cholesterol (primary hypercholesterolaemia - heterozygous-familial and non-familial) and mixed dyslipidaemia because of a lack of comparison data.
Although Praluent was effective in reducing LDL-c levels when compared with placebo, ezetimibe or statins in people with hypercholesterolaemia, the Institute was concerned that Praluent “had not been compared with the combination therapy of ezetimibe plus a statin, in the large population of people with non-familial hypercholesterolaemia”.