Drug news
NICE recommends Velcade (bortezomib) from Janssen Cilag VR-CAP combination to treat Mantle Cell Lymphoma- Janssen Cilag + Takeda Oncology
The National Institute for Health and Care Excellence (NICE) has recommended Velcade (bortezomib) from Janssen Cilag + Takeda Oncology, with rituximab, doxorubicin and prednisone (VR-CAP) as a treatment for previously untreated mantle cell lymphoma. The decision was based on the Phase III LYM 3002 study where the combination was shown to extend progression free survival (PFS) by 10.3 months compared to rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP). Patients in the VR-CAP combination had a median PFS of 24.7 months compared to 14.4 months for those treated with the R-CHOP combination.