The Incident Cohort Study shows home hemodialysis superior to peritoneal dialysis- NxStage Medical
NxStage Medical, Inc. is encouraging patients to consider home hemodialysis following a new study that found patient survivability rates are significantly higher with home hemodialysis (HHD) than peritoneal dialysis (PD). The Incident Cohort Study, the first of its size, was completed by the Australian and New Zealand Dialysis and Transplantation Registry and shows that the five-year survival rate for HHD is at 85 percent while the survival rate for PD patients is just 44 percent.
NxStage, believes the recent findings should inspire dialysis patients to ask their healthcare providers about home hemodialysis therapy with the System One. Currently, less than two percent of dialysis patients in the U.S. are performing HHD, versus approximately 9% performing PD.
Historically, studies comparing clinical outcomes between peritoneal dialysis and home hemodialysis have been limited. The Incident Cohort Study was the largest of its kind and assessed all Australian and New Zealand adult patients receiving home dialysis on day 90 after initiation of renal replacement therapy between 2000 and 2012. It included 10,710 patients on incident peritoneal dialysis and 706 patients on incident home hemodialysis and found that the risk of death-censored technique failure for HHD was 66 percent lower than PD. Directionally, these results were very consistent with recent presentations of survival and technique survival on NxStage HHD patients vs. PD in the US published by Weinhandl at the 2014 ASN Renal Week and 2015 NKC Spring Clinical Meeting.
In December 2014, NxStage obtained FDA clearance for nocturnal hemodialysis its System One, which it deems the first and only portable hemodialysis system cleared specifically for at-home and nighttime use.
See- Annie-Claire Nadeau-Fredette, Carmel M. Hawley, Elaine M. Pascoe, Christopher T. Chan, Philip A. Clayton, Kevan R. Polkinghorne, Neil Boudville, Martine Leblanc, and David W. Johnson- "An Incident Cohort Study Comparing Survival on Home Hemodialysis and Peritoneal Dialysis (Australia and New Zealand Dialysis and Transplantation Registry)"- CJASN CJN.00840115; published ahead of print June 11, 2015, doi:10.2215/CJN.00840115
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