Drug news
Afinitor success in BOLERO 2 study in advanced Breast Cancer
An interim analysis of a pivotal Phase III study BOLERO 2, showed Afinitor (everolimus) tablets from Novartis used in combination with exemestane significantly extended progression-free survival (PFS), or time without tumor growth, when compared to placebo plus exemestane in women with advanced breast cancer. The trial was stopped early after interim results showed the primary endpoint of PFS was met. The study included postmenopausal women with ER+HER2- metastatic breast cancer whose disease has progressed, despite initial endocrine therapy.