"Hyperammonaemia is a true neonatal emergency, with a high mortality and neurological complications in most survivors. It requires rapid and vigorous treatment"*

    "Hyperammonaemia is a true neonatal emergency with high 
  • Hyperammonaemia can cause severe neurological damage and death - what steps should you take?

    Review the guidelines section here...


    Video presentations from EAPS 2012 added to the hyperammonaemia video channel

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    Orphan Europe will be sponsoring a satellite symposium during the 6th Congress of the European Academy of Paediatric Societies (EAPS), in Geneva, Switzerland.

Welcome to the Hyperammonaemia Knowledge Centre. In this Knowledge Centre we provide an overview of hyperammonaemia and its metabolic causes including epidemiology, diagnosis, management and treatment options.

Hyperammonaemia (or hyperammonemia) is a condition associated with a number of inherited disorders. If not recognised and treated urgently it causes severe and permanent damage to the brain and the central nervous system. In order to provide optimal care for patients, it is essential that healthcare professionals involved in the diagnosis and management of hyperammonaemia have a thorough understanding of this condition.

,Hypoammonemia on-line resources

Hyperammonaemia e-learning

,Hyperammonaemia signs and symptoms