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Guideline

The management of newly diagnosed large B-cell lymphoma: A British Society for Haematology Guideline

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Last updated:20th Jan 2024
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The management of newly diagnosed large B-cell lymphoma: A British Society for Haematology Guideline


This BSH guideline summarises the recommended initial investigation and first-line management of large B-cell lymphoma (LBCL). Primary extra-nodal LBCL is discussed in this guideline, with the exception of lymphoma involving the central nervous system, covered by separate BSH guideline publications.1, 2 Post-transplant lymphoproliferative disorders are also covered by a separate guideline.3 The investigation and management of primary mediastinal large B-cell lymphoma, mediastinal grey-zone lymphoma, primary cutaneous LBCL, primary effusion lymphoma, plasmablastic lymphoma and Burkitt lymphoma are also beyond the scope of this guideline. The management of relapsed LBCL is covered in a separate guideline.


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