Latest news articles

Added 22 hours ago Drug news

BMS announces FDA breakthrough therapy designation for Orencia to help prevent acute graft-versus-host disease, a potentially life-threatening complication after stem cell transplant.- BMS

Bristol-Myers Squibb Company announced that the FDA has granted Breakthrough Therapy Designation for Orencia (abatacept) for the prevention of moderate...

Added 5 days ago Drug news

Naxitamab filed with the FDA in a rolling submission for high-risk neuroblastoma.- Y-mAbs Therapeutics

Y-mAbs Therapeutics announced that it has submitted to the FDA the first portions of its Biologics License Application for naxitamab...

Added 13 days ago Drug news

FDA approves Pentax Medical Video Duodenoscope ED34-i10T2 (DEC Duodenoscope).- Pentax Medical

The FDA has given marketing approval for the Pentax Medical Video Duodenoscope ED34-i10T2 (DEC Duodenoscope), the first duodenoscope with a...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

This guideline covers assessing and reducing the risk of venous thromboembolism (VTE or blood clots) and deep vein thrombosis (DVT) in people aged 16 and over in hospital.

Added 9 years ago

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart R

The scope of this focused update of the 2014 AF Guideline includes revisions to the section on anticoagulation (because of the approval of new medications and thromboembolism protection devices), revisions to the section...

Added 3 months ago

Urinary incontinence and pelvic organ prolapse in women: management

This guideline covers assessing and managing urinary incontinence and pelvic organ prolapse in women aged 18 and over. It also covers complications associated with mesh surgery for these conditions.

Added 3 months ago

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Journal articles

Functional benefit of smoking cessation in severe COPD patients undergoing bronchial valve implantation.

The aim of this study is to highlight the effectiveness of smoking cessation along with bronchial valve implantation in subjects with severe COPD.

Added 7 days ago

Advances in β-cell replacement therapy for the treatment of type 1 diabetes.

The main goal of treatment for type 1 diabetes is to control glycaemia with insulin therapy to reduce disease complications. For some patients, technological approaches to insulin delivery are inadequate, and allogeneic islet...

Added 9 days ago

Treatment challenges in pediatric Cushing's disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence.

Cushing’s disease (CD) is a rare endocrine condition caused by a corticotroph pituitary tumor that produces adrenocorticotropic hormone. The current state of knowledge of CD treatment is presented in this article including factors...

Added 10 days ago

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Clinical trials

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

This is a Phase 2 double-blind, randomized, placebo-controlled study to assess the safety and efficacy of ICV delivery of CT-010 via an implantable pump and a cranial port and dual lumen catheter (CIC) in subjects with focal seizures...

Added 10 days ago

Impact of Hyperoncotic Albumin to Support Blood Loss Replacement (HYPALB)

The primary objective of this study is to test the effect of 20% albumin on plasma volume expansion and fluid recruitment in the frame of blood loss replacement during cystectomy using established fluid kinetic models.

Added 8 months ago

This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding

The primary objective is to demonstrate reversal of the anticoagulant effect of dabigatran in patients treated with dabigatran etexilate who have uncontrolled or life-threatening bleeding requiring urgent intervention, and in patients treated...

Added 5 months ago

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Blog Posts

Professor Gerhard Pölzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 2 years ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

Hugh Harvey

Metrics Madness

Posted 4 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Yuli Pramana

Choosing Between Endoscopic Sclerotherapy And Endoscopic Ligation For Esophageal Varices

Posted 4 years ago

Endoscopic Sclerotherapy (ES) and Endoscopic Ligation (EL) were accepted in the treatment of esophageal varices bleeding in patients with liver cirrhosis. EL seemed to be superior to ES. If EL was difficult then ES should be performed.

CME

Fluid management in acutely ill patients

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
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1
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90

Assessing patients for minor surgery

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
0
Registration required
1
Subscription fee
15

Hidradenitis suppurativa: diagnosis and management

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
1
Registration required
1
Subscription fee
0
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