Latest news articles

Added 9 days ago Drug news

B-20 study of Oncotype DX Breast Recurrence Score test shows who to treat for breast cancer.- Genomic Health.

Genomic Health announced the publication of positive results from a new analysis of the NSABP-led B-20 study reconfirming that the...

Added 27 days ago Drug news

Real-world evidence on patients aged 80 and older presented from ARISTOPHANES study evaluating oral anticoagulants among patients with non-valvular atrial fibrillation- BMS + Pfizer

The Bristol-Myers Squibb-Pfizer Alliance presented new real-world evidence (RWE) from a sub-analysis of the ARISTOPHANES study comparing the safety and...

Added 2 months ago Drug news

FDA extends indication of Gardasil 9 for HPV to include women and men aged 27 through 45 years. Merck Inc.

The FDA has approved a supplemental application for Gardasil 9 (Human Papillomavirus (HPV) 9-valent Vaccine, Recombinant) expanding the approved use...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

VTE is a condition in which a blood clot (thrombus) forms in a vein. It most commonly occurs in the...

Added 8 years ago

Guidance document for prevention of Clostridium difficile infection in acute healthcare settings

This updated guideline provides a current review of the literature on interventions to control CDI in adult populations in acute healthcare settings and derives specific infection control recommendations.

Added 6 months ago

The Prevention of Early-onset Neonatal Group B Streptococcal Disease

The purpose of this guideline is to provide guidance for obstetricians, midwives and neonatologists on the prevention of early-onset (less than 7 days of age) neonatal group B streptococcal (EOGBS) disease...

Added 6 years ago

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Journal articles

Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis.

Objective: To evaluate whether baseline LDL-C level is associated with total and cardiovascular mortality risk reductions.

Added 3 months ago

Efficacy and Safety of Further Lowering of Low-Density Lipoprotein Cholesterol in Patients Starting With Very Low Levels: A Meta-analysis.

Objective: To evaluate efficacy and safety of further lowering LDL-C levels in patient populations presenting with median LDL-C levels of 1.8 mmol/L (70 mg/dL) or less.

Added 3 months ago

Global Prospective Safety Analysis of Rivaroxaban.

This study sought to assess the real-world safety profile of rivaroxaban through a pooled analysis of patients with AF enrolled in the XANTUS (Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation) program worldwide.

Added 3 months ago

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Clinical trials

Efficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A Participants (HAVEN 5)

This randomized, multicenter, open-label, Phase 3 study is designed to investigate the efficacy, safety, and pharmacokinetics of emicizumab in participants with hemophilia A regardless of factor VIII (FVIII) inhibitor status.

Added 9 months ago

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 Weeks in Participants With Hemophilia A (HAVEN 4)

This multicenter, open-label, non-randomized study will assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of emicizumab administered at a dose of 6 milligrams per kilogram (mg/kg) every 4 weeks...

Added 9 months ago

A Clinical Trial to Evaluate Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants Without Inhibitors (HAVEN 3)

This is a randomized, global, multicenter, open-label, Phase 3 clinical study in participants with severe hemophilia A without inhibitors against Factor VIII (FVIII) who are 12 years or older.

Added 9 months ago

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Blog Posts

Alex Keen

EPAD – Changing the way we think about Alzheimer’s prevention

Posted 4 months ago

We spoke to Professor Craig Ritchie of the University of Edinburgh, the poject co-coordinator for EPAD, a collaborative venture that is facilitating meaningful progress in preventative Alzheimer’s therapies. Find out more about the project, its methods, expectations and goals.

Alex Keen

ECCMID 2018 ‒ Antibiotic resistance: an immediate and growing threat

Posted 7 months ago

This year’s ECCMID is hosting a large number of sessions discussing antibiotic resistance, an immediate and pressing issue that has been described as ‘one of the biggest threats to global health, food security, and development today'.

Laura Quittenden

8 Common Water Contaminants and How to Prevent Them

Posted 10 months ago

When working in laboratories and hospitals, it’s crucial that any contaminants found in water are removed immediately, before they cause any damage.

CME

Measles: diagnosis and management

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Practice Pointer: Zika virus - management of infection and risk

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Breaking bad news: a how to do it guide

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Union of European Medical Specialists (via European Accreditation Council for CME)
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