Latest news articles

Added 15 days ago Drug news

BioMarin Pharma hassubmitted a MAA to the European Medicines Agency for valoctocogene roxaparvovec for adults with severe hemophilia A.

BioMarin Pharmaceutical Inc. has announced that the company submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA)...

Added 1 month ago Drug news

FDA approves Wilate for haemophilia A.- Octapharma

Octapharma USA announced the FDA has approved Wilate for treatment of adults and adolescents with hemophilia A for routine prophylaxis...

Added 2 months ago Drug news

Swedish Orphan Biovitrum AB (publ) (Sobi) has entered into an expanded agreement with Sanofi to exercise early opt-in for the development and commercialisation of BIVV 001 for the treatment of hemophilia A.

Swedish Orphan Biovitrum AB (publ) (Sobi) has entered into an expanded agreement with Sanofi to exercise early opt-in for the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Familial hypercholesterolaemia: identifification and management

This guideline covers identifying and managing familial hypercholesterolaemia (FH), a specific type of high cholesterol that runs in the family, in children, young people and adults. It aims to help identify people at increased risk of...

Added 1 day ago

Lyme disease

This guideline covers diagnosing and managing Lyme disease. It aims to raise awareness of when Lyme disease should be suspected and ensure that people have prompt and consistent diagnosis and treatment.

Added 1 year ago

The British Society of Gastroenterology/UKPBC primary biliary cholangitis treatment and management guidelines

Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in...

Added 1 year ago

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Journal articles

Evolving Concepts in Chronic Obstructive Pulmonary Disease Blood-Based Biomarkers.

In recent years, there has been a great deal of interest in the identification and validation of blood-based biomarkers for clinical use in chronic obstructive pulmonary disease (COPD).

Added 8 days ago

Diagnostic properties of total and free prostate-specific antigen to predict overall and clinically significant prostate cancer among men with low testosterone and prior negative biopsy.

Objective: To evaluate whether total serum PSA, free-PSA ratio and PSA density have similar diagnostic properties for detecting prostate cancer (PCa) and clinically-significant (cs) PCa in men with normal testosterone compared...

Added 18 days ago

Pan-ethnic carrier screening and prenatal diagnosis for spinal muscular atrophy: clinical laboratory analysis of >72,400 specimens.

Spinal muscular atrophy (SMA) is a leading inherited cause of infant death with a reported incidence of ∼1 in 10 000 live births and is second to cystic fibrosis as a common, life-shortening autosomal recessive disorder.

Added 24 days ago

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Clinical trials

Transperineal, MRI-guided, Prostate Biopsy

Primary purpose: Complications and rehospitalizations after transperineal prostate biopsy MRI-guided are reduced than transrectal prostate biopsies. Secondary purposes: - Patients...

Added 4 years ago

Rapid Medical Donation Programme for Breast Cancer (LEGACY)

Treatment of breast cancer has traditionally been based on the primary tumour's features in the breast. Only recently, when cancer...

Added 6 years ago

Non Ivasive Prenatal Diagnosis (NIPD) of Cystic Fibrosis

The purprose of this study is to develop and validate an analytical and clinical NIPD test for cystic fibrosis from...

Added 6 years ago

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Blog Posts

Laura Quittenden

8 Common Water Contaminants and How to Prevent Them

Posted 1 year ago

When working in laboratories and hospitals, it’s crucial that any contaminants found in water are removed immediately, before they cause any damage.

Hugh Harvey

Metrics Madness

Posted 4 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

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Breaking bad news: a how to do it guide

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Consent

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