Latest news articles

Added 1 day ago Drug news

NHS England will reimburse Hemlibra for prevention of bleeding episodes in hemophilia A patients who have factor VIII inhibitors. Roche

NHS England has approved the reimbursement of Hemlibra (emicizumab) from Roche for the prevention of bleeding episodes in adults and...

Added 1 month ago Drug news

BioMarin plans regulatory submissions for valoctocogene roxaparvovec to treat severe hemophilia A in 4Q 2019 in both U.S. and Europe

BioMarin Pharmaceutical Inc.announced that based on recent meetings with health authorities in the U.S. and Europe, the company plans to...

Added 1 month ago Drug news

Genentech presents a broad range of data for Hemlibra demonstrating continued benefits for people with Hemophilia A at the ISTH 2019 Congress

Genentech, a member of the Roche Group announced new data for Hemlibra (emicizumab-kxwh) across multiple pivotal studies in people with...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Lyme disease

This guideline covers diagnosing and managing Lyme disease. It aims to raise awareness of when Lyme disease should be suspected and ensure that people have prompt and consistent diagnosis and treatment.

Added 1 year ago

The British Society of Gastroenterology/UKPBC primary biliary cholangitis treatment and management guidelines

Primary biliary cholangitis (formerly known as primary biliary cirrhosis, PBC) is an autoimmune liver disease in which a cycle of immune mediated biliary epithelial cell injury, cholestasis and progressive fibrosis can culminate over time in...

Added 1 year ago

2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction

Treatment with amiodarone is associated with changes in thyroid function tests, but also with thyroid dysfunction (amiodarone-induced hypothyroidism, AIH, and amiodarone-induced thyrotoxicosis, AIT).

Added 1 year ago

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Journal articles

Growth Differentiation Factor 15 as a Biomarker in Cardiovascular Disease.

Background: Growth differentiation factor 15 (GDF-15) is expressed and secreted in response to inflammation, oxidative stress, hypoxia, telomere erosion, and oncogene activation. Cardiovascular (CV) disease is a major driver of...

Added 7 days ago

Serum C16:1n7/C16:0 ratio as a diagnostic marker for non-alcoholic steatohepatitis.

Background and Aims: Accurate diagnosis of non‐alcoholic steatohepatitis (NASH) from non‐alcoholic fatty liver disease (NAFLD) is clinically important. Therefore, there is a need for easier ways of diagnosing NASH.

Added 1 month ago

MACK-3 (combination of hoMa, Ast and CK18): A promising novel biomarker for fibrotic non-alcoholic steatohepatitis.

Introduction: MACK‐3 (combination of hoMa, Ast and CK18) was reported to be a good biomarker for the diagnosis of fibrotic non‐alcoholic steatohepatitis (NASH). However, there is no external validation to date.

Added 1 month ago

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Clinical trials

Transperineal, MRI-guided, Prostate Biopsy

Primary purpose: Complications and rehospitalizations after transperineal prostate biopsy MRI-guided are reduced than transrectal prostate biopsies. Secondary purposes: - Patients...

Added 4 years ago

Rapid Medical Donation Programme for Breast Cancer (LEGACY)

Treatment of breast cancer has traditionally been based on the primary tumour's features in the breast. Only recently, when cancer...

Added 6 years ago

Non Ivasive Prenatal Diagnosis (NIPD) of Cystic Fibrosis

The purprose of this study is to develop and validate an analytical and clinical NIPD test for cystic fibrosis from...

Added 6 years ago

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Blog Posts

Laura Quittenden

8 Common Water Contaminants and How to Prevent Them

Posted 1 year ago

When working in laboratories and hospitals, it’s crucial that any contaminants found in water are removed immediately, before they cause any damage.

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Confidentiality

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Breaking bad news: a how to do it guide

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Consent

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