Added 6 hours ago Drug news

CHMP recommends approval of Kalydeco in cystic fibrosis CFTR gene mutation.- Vertex Pharma

Vertex Pharmaceuticals (Europe) Limited announces that the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) adopted...

Added 24 days ago Drug news

European Commission approves Epidyolix for use as adjunctive therapy of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome.- GW Pharma

GW Pharmaceuticals plc , world leader in discovering, developing and commercialising cannabinoid prescription medicines, announces that the European Commission (EC)...

Added 1 month ago Drug news

Phase II/III Starbeam study of Lenti-D shows efficacy in cerebral adrenoleukodystrophy.- bluebird bio

bluebird bio announced updated results from the clinical development program for its investigational Lenti-D gene therapy in patients with cerebral...

ERS guidelines on the diagnosis and treatment of chronic cough in adults and children.

These guidelines incorporate the recent advances in chronic cough pathophysiology, diagnosis and treatment. The concept of cough hypersensitivity has allowed an umbrella term that explains the exquisite sensitivity of patients to external stimuli

Added 16 days ago

Preterm labour and birth

This guideline covers the care of women at increased risk of or with symptoms and signs of preterm labour (before 37 weeks) and women having a planned preterm birth.

Added 3 years ago

British Guideline on the Management of Asthma

The 2019 update includes a complete revision of the section on monitoring asthma including new information on predicting future risk of asthma attacks, and updates to the sections on pharmacological management of asthma

Added 5 years ago

Asthma exacerbation trajectories and their predictors in children with incident asthma.

Objective: To identify trajectories of asthma exacerbation and predictors of these trajectories in children with incident asthma.

Added 2 days ago

Nocturnal asthma is affected by genetic interactions between RORA and NPSR1.

Background: Neuropeptide S Receptor 1 (NPSR1) and Retinoid Acid Receptor‐Related Orphan Receptor Alpha (RORA) interact biologically, are both known candidate genes for asthma, and are involved in controlling...

Added 2 days ago

Anti-IgE treatment in allergic rhinitis.

Objectives: To review the efficacy of anti-IgE therapy in allergic rhinitis (AR).

Methods: Literature search was performed using...

Added 5 days ago

Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

The primary objective of the study is to examine the clinical efficacy of nusinersen administered intrathecally at higher doses to participants with spinal muscular atrophy (SMA).

Added 1 month ago

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

This 2-year study will evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) effects of ocrelizumab in children and adolescents ages >/= 10 to < 18 years with relapsing-remitting multiple sclerosis (RRMS).

Added 12 days ago

A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis (SMR3372)

Randomized, double blind, placebo controlled study. The study has two parts:
Dose-finding part, followed by longer term follow-up (6 months)

Added 2 days ago