Latest news articles
Added 3 days ago Drug news
FDA advisory committee recommends approval of Epidiolex for the adjunctive treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome .- GW Pharma.
GW Pharmaceuticals plc along with its U.S. subsidiary Greenwich Biosciences, announced that the Peripheral and Central Nervous System Drugs Advisory...
Added 1 month ago Drug news
EU approves Lokelma to treat hyperkalaemia.- AstraZeneca.
AstraZeneca announced that the European Commission has granted marketing authorisation for Lokelma (formerly ZS-9, sodium zirconium cyclosilicate) for the treatment...
Learning Zones
An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.
Hunter Syndrome
Hunter syndrome (MPS II) has symptoms which overlap with many common childhood complaints – do you know what to look for?
Cushing's Syndrome
Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?
+ 2 more
Cystic Fibrosis
View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.
+ 1 more
Hyperammonaemia
Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?
+ 2 more
Chronic Lymphocytic Leukaemia (CLL)
Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more
+ 1 more
Transplantation
See information on best practice in solid organ transplantation, and expert discussions on related hot topics.
Guidelines
Guidelines on Paediatric Urology
The majority of urological clinical problems in children are specialised and in many ways differ to those in adults. This publication intends to outline a practical and preliminary approach to paediatric urological conditions.
Added 2 years ago
BSH Guideline: management of thrombotic and haemostatic issues in paediatric malignancy
Venous thromboembolism (VTE) and bleeding are serious complications of cancer and its treatment. A recent survey of UK paediatric haematologists and oncologists identified a broad variety of practice in the management of issues...
Added 1 month ago
Autism spectrum disorder: Consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology
An expert review of the aetiology, assessment, and treatment of autism spectrum disorder, and recommendations for diagnosis, management and service provision was coordinated by the British Association for Psychopharmacology, and evidence graded.
Added 1 month ago
Journal articles
Levetiracetam monotherapy for the treatment of infants with epilepsy.
Purpose: Levetiracetam is a broad-spectrum anti-epileptic drug that is effective against both focal and generalized epilepsies. In this study, we aimed to evaluate the efficacy, tolerability and safety of levetiracetam monotherapy...
Added 1 day ago
A meta-analysis of randomized controlled trials on levetiracetam in the treatment of pediatric patients with epilepsy.
Objective: To evaluate clinical efficacy, safety, and tolerability of levetiracetam as mono- or adjunctive therapy in the treatment of children and adolescents with epilepsy.
Added 1 day ago
Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib.
Purpose: Vandetanib is well-tolerated in patients with advanced medullary thyroid carcinoma (MTC). Long-term outcomes and mechanisms of MTC progression have not been reported previously.
Added 4 days ago
Clinical trials
Efficacy, Safety, and Pharmacokinetic Study of Prophylactic Emicizumab Versus No Prophylaxis in Hemophilia A Participants (HAVEN 5)
This randomized, multicenter, open-label, Phase 3 study is designed to investigate the efficacy, safety, and pharmacokinetics of emicizumab in participants with hemophilia A regardless of factor VIII (FVIII) inhibitor status.
Added 1 month ago
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 Weeks in Participants With Hemophilia A (HAVEN 4)
This multicenter, open-label, non-randomized study will assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of emicizumab administered at a dose of 6 milligrams per kilogram (mg/kg) every 4 weeks...
Added 1 month ago
Bioavailability and Pharmacokinetics of Intranasal Dexmedetomidine in Children
We aim to characterize the bioavailability and pharmacokinetics of dexmedetomidine after intranasal dosing employing pharmacometric methods in otherwise healthy 1 month to 11 years of age children scheduled...
Added 1 year ago
Blog Posts
Heather Lander, PhD
Zika Virus: old lessons from a newly emerging pathogen
Posted 2 years ago
Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.
Am Ang Zhang
Autism: Challenges and Obstacles!
Posted 2 years ago
Retired child psychiatrist Am Ang Zhang discusses his experiences of working with the families of autistic children.
Am Ang Zhang
Autism: Frances Tustin and Entrenchment!
Posted 2 years ago
Am Ang Zhang discusses his work with pioneering child psychotherapist Frances Tustin, and his observations of entrenchment in autistic children.
CME
The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test
- Accrediting body
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BMJ Learning - British Medical Learning
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Idiopathic constipation and nocturnal enuresis in childhood: a guide to management: putting NICE guidelines into practice
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BMJ Learning - British Medical Learning
- Credits available
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- 1
- Subscription fee
- 90
Managing Symptomatic Asthma
- Accrediting body
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Union of European Medical Specialists (via European Accreditation Council for CME)
- Credits available
- 1
- Registration required
- 1
- Subscription fee
- FREE