Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 19 hours ago Drug news

REFLECTIONS B7391003 study, of biosimilar PF-06439535 versus Avastin (bevacizumab), met its primary objective for treatment of NSCLC.- Pfizer

Pfizer Inc. announced that the REFLECTIONS B7391003 study, a comparative, confirmatory safety and efficacy study of PF-06439535 versus Avastin (bevacizumab),...

Added 19 hours ago Drug news

Phase III trial of Keytruda (pembrolizumab) fails to meet primary endpoint in head and neck cancer- Merck Inc

Merck Inc announced that the pivotal phase III KEYNOTE-040 trial investigating Keytruda (pembrolizumab), in previously treated patients with recurrent or...

Added 19 hours ago Drug news

FDA accepts supplemental filing sBLA for Opdivo (nivolumab) dosing every four weeks for all indications.- BMS

Bristol-Myers Squibb Company has announced that the FDA accepted its supplemental Biologics License Applications (sBLAs) to update Opdivo (nivolumab) dosing...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Breakthrough Cancer Pain Learning Zone

Invitation to watch the online broadcast of the BeCOn OWN event 'Shifting paradigms in BTcP management' on June 16 2017.

Visit Breakthrough Cancer Pain Learning Zone


Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

Visit Chronic Lymphocytic Leukaemia (CLL)


Prostate Cancer

How can you balance the harmful effects of treatment with control of prostate cancer growth in otherwise healthy patients?

Visit Prostate Cancer


What's on the horizon?

Marshall Pearce

Antibody-drug conjugates (ADCs)

Over the past couple of decades, there have been advances in a class of drugs which for a long time was purely theoretical: antibody-drug conjugates (ADCs). The concept underlying ADCs is elegant – what if it were possible to ‘target’ particular groups of cells with a cytotoxic agent, rather than exposing every cell of the body to it?

Marshall Pearce

Cancer immunotherapies

It was the winner of the 1908 Nobel prize for medicine, Paul Ehrlich, who is first credited with discussing the concept of a “magic bullet”, able to target specific cells without damaging healthy tissue. With the advent of immunotherapy, as well as antibody-drug conjugates, we are beginning to realise this vision.

Guidelines

Breast screening: clinical guidelines for screening assessment

The aim of assessment is to obtain a definitive and timely diagnosis of all potential abnormalities detected during screening.

Added 2 months ago

ESMO Consensus Conference on Malignant Lymphoma: General Perspectives and Recommendations for Prognostic Tools in Mature B-cell Lymphomas and Chronic Lymphocytic Leukaemia

In order to complement the already available European Society for Medical Oncology (ESMO) Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with malignant lymphomas, ESMO organised a consensus conference...

Added 9 months ago

NCCN Clinical Practice Guidelines in Oncology: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia

CLL remains the most prevalent adult lerkemia in Wester countries but is considered rare in regions such as East Asia. CLL/SLL comprises approximately 7% of newly diagnosed cases of NHL.

Added 9 months ago

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Journal articles

Abiraterone for prostate cancer not previously treated with hormone therapy

Abiraterone acetate plus prednisolone improves survival in men with relapsed prostate cancer.

Added 9 days ago

New drugs in acute myeloid leukemia.

The standard therapy for acute myeloid leukemia (AML) has not changed meaningfully for the past four decades.

Added 20 days ago

Novel drug therapies in myeloid leukemia.

Both acute myeloid leukemia and chronic myeloid leukemia are thought to arise from a subpopulation of primitive cells, termed leukemic stem cells

Added 20 days ago

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Clinical trials

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 3 months ago

Study of abiraterone acetate plus ADT versus apalatumide versus abiraterone and apalatumide in patients with advanced prostate cancer with non-castrate testosterone levels

Evaluation of the activity, safety and patients reported outcome of ADT plus abiraterone, abiraterone plus APALUTAMIDE (a second-generation antiandrogen) or APALUTAMIDE alone in hormone naïve locally advanced...

Added 9 months ago

Olaparib with or without cediranib in treating patients with metastatic hormone-resistant prostate cancer

This randomized phase II trial studies how well olaparib with or without cediranib works in treating patients with hormone-resistant prostate cancer that has spread to other places in the body.

Added 9 months ago

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Blog Posts

Fiona Holland

What to say and do when someone has cancer

Posted 5 months ago

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Treatment Optimisation in Chronic Lymphocytic Leukaemia

Treatment Optimisation in Chronic Lymphocytic Leukaemia
Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
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1
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FREE

Managing the side effects of treatment for prostate cancer

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Managing patients at risk of prostate cancer

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
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