Latest news articles

Added 9 hours ago Drug news

FDA approves Piqray + fulvestrant to treat hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-), PIK3CA-mutated, advanced or metastatic breast cancer.- Novartis

Novartis announced the FDA has approved Piqray (alpelisib, formerly BYL 719) in combination with fulvestrant for the treatment of postmenopausal...

Added 6 days ago Drug news

Twirla is refiled with FDA as contraceptive patch

Agile Therapeutics has resubmitted to the FDA the NDA for its lead product candidate, Twirla, an investigational low-dose combined hormonal...

Added 6 days ago Drug news

Additional data from SOPHIA study of margetuximab for HER2-positive metastatic breast cancer

MacroGenics, Inc.,has announced additional details of the results from the Phase III SOPHIA study of margetuximab in patients with HER2-positive...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Added 7 months ago

Antenatal and postnatal mental health: clinical management and service guidance

This guideline covers recognising, assessing and treating mental health problems in women who are planning to have a baby, are pregnant, or have had a baby or been pregnant in the past year.

Added 4 years ago

Heavy menstrual bleeding: assessment and management

This guideline covers assessing and managing heavy menstrual bleeding (menorrhagia).

Added 12 years ago

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Journal articles

Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

We aimed to measure levels and track trends in maternal mortality, the key causes contributing to maternal death, and timing of maternal death with respect to delivery.

Added 2 days ago

Coagulation assessment by rotation thrombelastometry in normal pregnancy.

We analysed changes in coagulation during normal pregnancy with a novel point-of-care device based on thrombelastometry (ROTEM). We compared the results obtained with those of standard coagulation tests in 104 patients...

Added 2 days ago

Treatment of Postpartum Hemorrhage With Blood Products in a Tertiary Hospital: Outcomes and Predictive Factors Associated With Severe Hemorrhage.

Postpartum hemorrhage (PPH) remains a leading cause of maternal mortality and morbidity worldwide. This retrospective observational study describes patient characteristics and hemostatic therapies administered to 352 parturients...

Added 2 days ago

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Clinical trials

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- Intermediate Risk Early Breast Cancer (EarLEE-2)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 1 year ago

Adjuvant Ribociclib With Endocrine Therapy in Hormone Receptor+/HER2- High Risk Early Breast Cancer (EarLEE-1)

This is an international, multi-center, randomized, double-blinded, placebo-controlled clinical study evaluating the efficacy and safety of ribociclib with endocrine therapy as an adjuvant treatment in patients with hormone receptor-positive...

Added 1 year ago

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. (OlympiAD)

This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice of capecitabine, vinorelbine or eribulin in...

Added 1 year ago

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Blog Posts

Allen Wellings

EBCC 2018 – Roundup of this year's conference

Posted 1 year ago

At the recent European Breast Cancer Conference the best and brightest in breast cancer research and care met to present and discuss the latest breakthroughs. Brief summaries of some of the key abstracts are found here.

Alex Keen

EBCC 2018 – The multidisciplinary approach to breast cancer care

Posted 1 year ago

The focus of this year’s European Breast Cancer Conference is the importance of multidisciplinary working. Explore the origins of multidisciplinary cancer care and the evidence surrounding it. 

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Testosterone treatment, consultation length and IUD fitting: journals update March 2017

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MIMS Learning - Monthly Index of Medical Specialities
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Zika virus

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Step by step: diabetes in pregnancy

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BMJ Learning - British Medical Learning
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