Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 8 hours ago Drug news

Phase III study of Intuniv (guanfacine hydrochloride prolonged release) meets primary endpoint in adults with attention deficit hyperactivity disorder.- Shire + Shionogi.

Shire and Shionogi announced that a Phase III study evaluating Intuniv (guanfacine hydrochloride prolonged release) in adult patients with attention...

Added 8 hours ago Drug news

APOLLO phase III study of ALN TTR02 (patisiran) in hereditary ATTR amyloidosis with polyneuropathy meets primary endpoints.- Sanofi Genzyme + Alnylam Pharmaceuticals.

Sanofi Genzyme and Alnylam Pharmaceuticals announced that the APOLLO Phase III study of ALN TTR02 (patisiran), for patients with hereditary...

Added 8 hours ago Drug news

Medtronic launches Intellis spinal cord neurostimulation platform which includes the world’s smallest fully implantable spinal cord neurostimulator to treat pain.

Medtronic received 510(k) FDA approval on 11 July 2017 and is now releasing in the U.S. its Intellis spinal cord...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Breakthrough Cancer Pain Learning Zone

Invitation to watch the online broadcast of the BeCOn OWN event 'Shifting paradigms in BTcP management' on June 16 2017.

Visit Breakthrough Cancer Pain Learning Zone

Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Chronic Obstructive Pulmonary Disease (COPD)

View highlights from recent congresses presented in new expert videos with leading physicians.

+ 3 more

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Guidelines

Guidelines on Chronic Pelvic Pain

This guideline plays an important role in the process of consolidation and improvement of care for patients with abdominal and...

Added 1 year ago

Guidelines on Neuro-Urology

The European Association of Urology (EAU) Neuro-Urology Guidelines aim to provide information for clinical practitioners on the incidence, definitions, diagnosis,...

Added 1 year ago

Spinal injury: assessment and initial management

This guideline covers the assessment and early management of spinal column and spinal cord injury in pre-hospital settings (including ambulance...

Added 1 year ago

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Journal articles

The Desmopressin test in the differential diagnosis between Cushing’s Disease and pseudo-Cushing states

Differentiating Cushing's disease (CD) from pseudo-Cushing (PC) states may still be difficult in current practice.

Added 6 days ago

Comparison of the dexamethasone-suppressed corticotropin-releasing hormone test and low-dose dexamethasone suppression test in the diagnosis of Cushing’s syndrome

The low-dose dexamethasone suppression test (LDDST) is widely used in confirming a diagnosis of Cushing's syndrome. 

Added 6 days ago

The Metyrapone and Dexamethasone Suppression Tests for the Differential Diagnosis of the Adrenocorticotropin-dependent Cushing Syndrome: A Comparison

To develop criteria for interpreting results of the metyrapone test for the differential diagnosis of the adrenocorticotropin (ACTH)-dependent Cushing syndrome.

Added 6 days ago

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Clinical trials

Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

The purpose of this study is to determine whether aFT218 is safe and effective for the treatment of excessive daytime...

Added 2 years ago

Pembrolizumab Plus Bevacizumab for Treatment of Brain Metastases in Metastatic Melanoma or Non-small Cell Lung Cancer

The purpose of this phase 2 trial is to study the activity of pembrolizumab in combination with bevacizumab in patients...

Added 2 years ago

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

To assess the safety and tolerability of rovalpituzumab tesirine in subjects with specific delta-like protein 3-expressing advanced solid tumors.

Added 2 years ago

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Blog Posts

Heather Lander, PhD

Zika Virus: old lessons from a newly emerging pathogen

Posted 1 year ago

Virologist-turned-Science Writer, Dr. Heather Lander, discusses the emergence of Zika virus and what we know so far.

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Bob Bury

Community Mental Health Provision then and now - is all progress positive?

Posted 3 years ago

Bob Bury muses on the state of modern mental healthcare. Instead of asylums, patients are now part of the community. But what of those who fall through the cracks? How can GPs help patients who need emergency mental health care? Can we learn anything from the methods of the past? Are three letter acronyms helpful? Examining the politics and hurdles of the UK's modern Community Mental Health provision, Bob Bury questions what UK healthcare professionals can do better and how things should change.

CME

Chest x ray: an essential guide to interpretation

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Tricyclic antidepressants and headaches: systematic review and meta-analysis

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Breaking bad news: a how to do it guide

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