Latest news articles

Added 1 day ago Drug news

NICE requests Biogen to submit Spinraza for single technology appraisal as a treatment for spinal muscular atrophy.

The National Institute for Health and Care Excellence (NICE) has formally invited Biogen to submit Spinraza (nusinersen) for Single Technology...

Added 11 days ago Drug news

Data from phase III TOLEDO study of APO-go/Movapo in Parkinsons disease published in Lancet Neurology.- Britannia Pharma.

Britannia Pharma announced publication of the results of the double-blind phase of the phase III TOLEDO study of APO-go/Movapo (apomorphine)...

Added 15 days ago Drug news

Laquinimod in Phase II LEGATO-HD trial to treat Huntington's disease did not met its primary endpoint.- Active Biotech + Teva.

Active Biotech provided an update regarding the clinical development of laquinimod by Teva Pharmaceutical Industries Ltd. The Phase II LEGATO-HD...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Fractures (complex): assessment and management

This guideline covers assessing and managing pelvic fractures, open fractures and severe ankle fractures (known as pilon fractures and intra-articular...

Added 2 years ago

EULAR recommendations for the use of imaging in the clinical management of peripheral joint osteoarthritis

These evidence-based recommendations and related research agenda provide the basis for sensible use of imaging in routine clinical assessment of people with OA.

Added 1 month ago

Update of EULAR recommendations for the treatment of systemic sclerosis

These updated data-derived and consensus-derived recommendations will help rheumatologists to manage patients with SSc in an evidence-based way. These recommendations also give directions for future clinical research in SSc.

Added 1 month ago

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Journal articles

Review of Biosimilar Trials and Data on Adalimumab in Rheumatoid Arthritis.

In this article, we recap the evidence from bio-originator trials in rheumatoid arthritis (RA) to provide context for a critical review of biosimilar trial data.

Added 1 day ago

Prevalence of psoriatic arthritis in patients with psoriasis: A systematic review and meta-analysis of observational and clinical studies.

Objectives: To assess the prevalence and incidence of PsA in patients with psoriasis.

Added 14 days ago

Sublingual sufentanil for postoperative pain relief: first clinical experiences.

The sublingual sufentanil tablet system (SSTS) is a novel hand-held patient-controlled analgesia device developed for treatment of moderate-to-severe postoperative pain. Here we present the first results of its clinical use.

Added 28 days ago

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Clinical trials

A Study to Investigate Different Doses of BAY1213790 to Prevent Blood Clots in Patients Undergoing Elective Total Knee Replacement Surgery (FOXTROT)

This study is to compare the study drug BAY1213790 to existing therapies, ie Enoxaparin or Apixaban for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).

Added 9 months ago

Study of Cingalâ„¢ for the Relief of Knee Osteoarthritis Compared to Triamcinolone Hexacetonide

This is a multi-center, randomized, double-blind, parallel group, active comparator controlled trial to evaluate the efficacy and safety of a single injection of Cingal for the relief of joint pain in subjects with OA of the knee.

Added 1 month ago

Study of the Safety, Pharmacodynamics (PD) and Efficacy of KRN23 in Children From 1 to 4 Years Old With X-linked Hypophosphatemia (XLH)

UX023-CL205 is a multicenter, open-label, Phase 2 study in children from 1 to 4 years old with XLH to assess the safety, PD, and efficacy of KRN23 administered via subcutaneous (SC) injections every 2 weeks (Q2W) for a total of 160 weeks.

Added 4 months ago

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Blog Posts

Alex Keen

EULAR 2018 – Biosimilars: the future of rheumatology?

Posted 2 months ago

EULAR's Annual European Congress of Rheumatology aims to encourage innovation and collaboration across all aspects of rheumatology, something that is particularly well illustrated by biologics and their more affordable counterpart, biosimilars. Could they unlock the door to accessible, life-changing treatment for millions more?

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Physical impairments in symptomatic femoroacetabular impingement: a systematic review of the evidence

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Breaking bad news: a how to do it guide

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Pressure ulcers: assessment and management

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