Latest news articles

Added 21 hours ago Drug news

Phase II BLAST Study shows median overall survival of 36.5 months in patients with minimal residual disease positive acute lymphoblastic leukemia

Amgen has announced the five-year overall survival (OS) analysis from the single-arm, Phase II BLAST study that evaluated Blincyto (blinatumomab)...

Added 1 day ago Drug news

Phase III ASCEND trial showed Calquence prolonged the time patients live without disease progression in chronic lymphocytic leukaemia (CLL)

AstraZeneca announced detailed results from the interim analysis of the Phase III ASCEND trial at the European Hematology Association (EHA)...

Added 1 day ago Drug news

Phase III study of Ultomiris shows efficacy and safety in paroxysmal nocturnal hemoglobinuria.

Alexion Pharmaceuticals announced the presentation of new data demonstrating that Ultomiris (ravulizumab) provided consistent efficacy and safety through 52 weeks...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

+ 2 more

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

+ 1 more

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

British Thoracic Society Guideline for the initial outpatient management of pulmonary embolism (PE)

The British Thoracic Society (BTS) Guideline for the initial OP management of PE provides guidance on how to risk-stratify patients with suspected and confirmed PE and subsequently manage them in an OP or ambulatory care setting.

Added 11 months ago

EASL Clinical Practice Guidelines on hepatitis E virus infection

Infection with hepatitis E virus (HEV) is a significant cause of morbidity and mortality, representing an important global health problem. Our understanding of HEV has changed completely over the past decade.

Added 11 months ago

2018 update of the EULAR recommendations for the management of Behçet’s syndrome

These updated, evidence-based recommendations are intended to help physicians caring for patients with BS.

Added 11 months ago

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Journal articles

Type 1 and 2 diabetes mellitus: A review on current treatment approach and gene therapy as potential intervention.

Type 1 and type 2 diabetes mellitus is a serious and lifelong condition commonly characterised by abnormally elevated blood glucose levels due to a failure in insulin production or a decrease in insulin sensitivity and function.

Added 4 days ago

Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review.

Aim of the review: This article reviewed findings on medicinal plants with both anti-diabetic and anti-hypertensive effects reported in same experimental study to facilitate the development of dual-acting therapies against...

Added 4 days ago

An update on the safety of SGLT2 inhibitors.

Areas covered: This narrative review discusses the safety profile of SGLT2is: initial concerns (cardiovascular safety, acute renal failure, hypoglycemia, urinary and genital infections, volume depletion, bladder cancer)...

Added 4 days ago

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Clinical trials

Dose-finding Study for SAR442168 in Relapsing Multiple Sclerosis

To determine the efficacy of SAR442168 in reducing the number of new brain lesions reported in Magnetic Resonance Imaging (MRI)

Added 7 days ago

Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric Participants

The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both compared with placebo, in pediatric participants with RRMS.

Added 7 days ago

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

The purpose of the study is to evaluate the efficacy, safety and tolerability of the 3 selected dose regimens of padsevonil (PSL) administered concomitantly with up to 3 anti-epileptic drugs (AEDs) compared with placebo for treatment...

Added 19 days ago

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Blog Posts

Adam Jeffery

What is Overdiagnosis?

Posted 1 month ago

Overdiagnosis is the diagnosis of disease that will cause neither morbidity nor mortality during a patient’s lifetime. Doctors are trained to listen, examine, test, diagnose and treat patients, but we are not warned of the possible dangers of “diseases”, the diagnosis of which will not benefit the patient and may also lead to harm. I would argue that the Hippocratic oath, in particular “Primum non nocere” (first, do no harm) should be at the forefront of every clinician’s mind when seeing patients.

Alex Keen

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

Posted 1 year ago

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.

Alex Keen

ISICEM 2018 – The Sepsis Six and BUFALO

Posted 1 year ago

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

CME

Treatment Optimisation in Chronic Lymphocytic Leukaemia

Treatment Optimisation in Chronic Lymphocytic Leukaemia
Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
FREE

Anticoagulation

Accrediting body
BJC Learning
Credits available
5
Registration required
1
Subscription fee
0

Personalisation of chronic lymphocytic leukaemia (CLL) care

Personalisation of chronic lymphocytic leukaemia (CLL) care
Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
FREE
Search all CME for Internal medicine