Data from multiple sources - Curated by Toby Galbraith - Last updated 13 April 2017

Latest news articles

Added 18 hours ago Drug news

CytRx Corporation agrees on preparations for a New Drug Application (NDA) submission for aldoxorubicin in soft tissue sarcomas (STS).

CytRx Corporation has announced the FDA has reached an agreement with CytRx on preparations for a New Drug Application (NDA)...

Added 18 hours ago Drug news

EU CHMP recommends approval of Besponsa (inotuzumab ozogamicin) for treating acute lymphoblastic leukaemia- Pfizer

The Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation...

Added 1 day ago Drug news

Amgen files sBLA with FDA and application for variation of MAA with EMA for Xgeva (denosumab) to prevent skeletal-related events (SREs) in solid tumors to include patients with multiple myeloma.-Amgen

Amgen has announced the submission of a supplemental Biologics License Application (sBLA) to the FDA and an application for a...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Bedwetting

Essential screening, diagnosis and best strategies to manage bedwetting

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Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

Visit Chronic Lymphocytic Leukaemia (CLL)

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients

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Guidelines

American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia and prevention of atherosclerosis.

The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees.

Added February 2017 ago

NCCN Clinical Practice Guidelines in Oncology: Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia

CLL remains the most prevalent adult lerkemia in Wester countries but is considered rare in regions such as East Asia. CLL/SLL comprises approximately 7% of newly diagnosed cases of NHL.

Added October 2016 ago

British Guideline on the Management of Asthma

Asthma is a common condition which produces a significant workload for general practice, hospital outpatient clinics and inpatient admissions.

Added October 2014 ago

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Journal articles

Idelalisib for the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma.

Idelalisib is a first-in-class selective oral PI3Kδ inhibitor for the treatment of patients with relapsed chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma, a predominantly elderly population with high comorbidity.

Added April 2017 ago

Outcomes of patients with chronic lymphocytic leukemia treated with first-line idelalisib plus rituximab after cessation of treatment for toxicity.

Background: More active therapies are needed for older and unfit patients with chronic lymphocytic leukemia (CLL) who are not eligible for chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab.

Added April 2017 ago

Idelalisib in the management of lymphoma.

Inhibition of the phosphatidylinositol-3-kinase (PI3K) pathway as an anticancer therapeutic strategy was realized with the approval of the orally bioavailable small molecule PI3Kδ inhibitor idelalisib.

Added April 2017 ago

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Clinical trials

Comparison of Propofol and Dexmedetomidine to Treat Hyperactive and Mixed ICU Delirium - the Basel ProDex Randomized Trial

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am...

Added January 2017 ago

Study of abiraterone acetate plus ADT versus apalatumide versus abiraterone and apalatumide in patients with advanced prostate cancer with non-castrate testosterone levels

Evaluation of the activity, safety and patients reported outcome of ADT plus abiraterone, abiraterone plus APALUTAMIDE (a second-generation antiandrogen) or APALUTAMIDE alone in hormone naïve locally advanced...

Added January 2017 ago

Olaparib with or without cediranib in treating patients with metastatic hormone-resistant prostate cancer

This randomized phase II trial studies how well olaparib with or without cediranib works in treating patients with hormone-resistant prostate cancer that has spread to other places in the body.

Added December 2016 ago

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Blog Posts

Fiona Holland

What to say and do when someone has cancer

Posted 2 months ago

Ahead of World Cancer Day on Saturday (February 4), Fiona Holland, Psychology Lecturer, discusses what to say and what not to say to someone with cancer.

Liam Farrell

Bad smells are good

Posted 6 months ago

Delicacy is not a virtue in this job.

Monica Caliber

Hypogonadism – why important to diagnose and treat?

Posted 8 months ago

Most clinicians and patients think that the purpose of treating hypogonadism is to merely relieve symptoms. However, this only scratches the surface... 

CME

Survival guide: safe prescribing for surgical inpatients

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Carcinoma of unknown primary origin: diagnosis and management: putting NICE guidelines into practice

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Treatment Optimisation in Chronic Lymphocytic Leukaemia

Treatment Optimisation in Chronic Lymphocytic Leukaemia
Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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