Latest news articles

Added 9 days ago Drug news

Pooled analysis of data from three phase II/III randomized clinical trials on the use of rescue medications with Zilretta

Flexion Therapeutics, Inc. announced that a pooled analysis of data from three Phase II/III randomized clinical trials on the use...

Added 11 days ago Drug news

BC 3781 file with EU for community-acquired pneumonia

Nabriva Therapeutics announced that the Company’s marketing authorization application (MAA) for both the intravenous (IV) and oral formulations of BC...

Added 12 days ago Drug news

Study shows reduced incidence of post operative cystoid macular edema with Omidria

Omeros Corporation announced the results of a real-world clinical study showing that its FDA-approved ophthalmic drug Omidria (phenylephrine and ketorolac...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Psoriasis

Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more.

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Guidelines

Age-related macular degeneration

This guideline covers diagnosing and managing age-related macular degeneration (AMD) in adults. It aims to improve the speed at which people are diagnosed and treated to prevent loss of sight.

Added 11 months ago

Cataracts in adults: management

This guideline covers managing cataracts in adults aged 18 and over. It aims to improve care before, during and after cataract surgery by optimising service organisation, referral and surgical management, and reducing complications.

Added 11 months ago

Parkinson’s disease in adults

This guideline covers diagnosing and managing Parkinson's disease in people aged 18 and over. It aims to improve care from the time of diagnosis, including monitoring and managing symptoms...

Added 11 months ago

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Journal articles

Gray Matter Changes Associated With the Development of Delusions in Alzheimer Disease.

Objective: Delusions affect approximately a third of Alzheimer disease (AD) patients and are associated with poor outcomes. Previous studies investigating the neuroanatomic correlates of delusions have yet to reach a consensus...

Added 5 days ago

A novel therapeutic potential of cysteinyl leukotrienes and their receptors modulation in the neurological complications associated with Alzheimer's disease.

Cysteinyl leukotrienes (cysLTs) are member of eicosanoid inflammatory lipid mediators family produced by oxidation of arachidonic acid by action of the enzyme 5-lipoxygenase (5-LOX). 5-LOX is activated by enzyme...

Added 5 days ago

A vaccine against Alzheimer`s disease: anything left but faith?

Areas covered: We provide an overview of the molecular pathology that leads to an increase in Aβ peptide accumulation, of the mechanism of action for antibody mediated therapies and of the therapeutic vaccines that target...

Added 5 days ago

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Clinical trials

GAIN Trial: Phase 2/3 Study of COR388 in Subjects With Alzheimer's Disease

This is a randomized, double-blind, placebo-controlled study that will assess the efficacy, safety, and tolerability of 2 dose levels of COR388 in subjects with a clinical diagnosis of mild to moderate AD dementia.

Added 5 days ago

Study of BHV-4157 in Alzheimer's Disease (T2 Protect AD)

Preclinical models suggest that riluzole, the active metabolite of BHV-4157, may protect from AD-related pathology and cognitive dysfunction. Titrated dose of BHV-4157 to 280 mg, or placebo, taken orally once daily.

Added 5 days ago

ANAVEX2-73 for Treatment of Early Alzheimer's Disease

Phase 2b/3 48-week study to evaluate the effects of ANAVEX2-73 on cognition and function after 48 weeks of daily treatment. Additional outcome measures include refined measures of sleep, behavioral and psychological symptoms...

Added 5 days ago

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Blog Posts

Alex Keen

EPAD – Changing the way we think about Alzheimer’s prevention

Posted 9 months ago

We spoke to Professor Craig Ritchie of the University of Edinburgh, the poject co-coordinator for EPAD, a collaborative venture that is facilitating meaningful progress in preventative Alzheimer’s therapies. Find out more about the project, its methods, expectations and goals.

Laura Quittenden

World COPD Day: What is COPD and what causes it?

Posted 1 year ago

Today marks the annual World COPD Day, a day dedicated to increasing awareness of a disease that affects 65 million people around the globe. 

 

We've summarised the causes, complications and statistics surrounding COPD in this handy 2 minute read.

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

What's new in chronic heart failure

Accrediting body
BMJ Learning - British Medical Learning
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90

Older lady with uncontrolled COPD

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
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0

Step by step: A guide to diagnosing heart failure

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
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