Latest news articles

Added 2 days ago Drug news

Phase III VISIBLE 1 trial of subcutaneous Entyvio meets endpoint in ulcerative colitis.- Takeda.

Takeda has announced that the Phase III VISIBLE 1 trial of investigational subcutaneous formulation Entyvio (vedolizumab) for patients with ulcerative...

Added 2 days ago Drug news

Phase III MORA trial of Plenvu in bowel preparation published in Endoscopy.- Norgine.

Norgine announced that results from the Plenvu (polyethylene glycol based bowel preparation) Phase III MORA trial were published in ENDOSCOPY,...

Added 3 days ago Drug news

Tecentriq + Avastin combination in Phase III trial to treat Liver Cancer.- Genentech + Roche.

Genentech now reports that earlier this year, Genentech initiated IMbrave150 (NCT03434379), an open-label, multicenter, randomized Phase III study investigating the...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Cystic Fibrosis Knowledge Centre

Cystic Fibrosis Knowledge Centre

View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines.

Inflammatory Bowel Disease Knowledge Centre

Inflammatory Bowel Disease Knowledge Centre

The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and unmet needs and the underlying inflammatory processes that drive IBD, considering some of the key inflammatory pathways.

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Guidelines

EASL Clinical Practice Guidelines on hepatitis E virus infection

Infection with hepatitis E virus (HEV) is a significant cause of morbidity and mortality, representing an important global health problem. Our understanding of HEV has changed completely over the past decade.

Added 1 month ago

UK guidelines on oesophageal dilatation in clinical practice

These guidelines deal specifically with the dilatation procedure using balloon or bougie devices as a primary treatment strategy for non-malignant narrowing of the oesophagus.

Added 1 month ago

2018 update of the EULAR recommendations for the management of Behçet’s syndrome

These updated, evidence-based recommendations are intended to help physicians caring for patients with BS.

Added 1 month ago

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Journal articles

Golimumab effectiveness and safety in clinical practice for moderately active ulcerative colitis.

Golimumab (GLB) is an antitumour necrosis factor-α (anti-TNF) therapy that has shown efficacy as induction and maintenance therapy for ulcerative colitis (UC).

Added 2 days ago

Sublingual sufentanil for postoperative pain relief: first clinical experiences.

The sublingual sufentanil tablet system (SSTS) is a novel hand-held patient-controlled analgesia device developed for treatment of moderate-to-severe postoperative pain. Here we present the first results of its clinical use.

Added 2 days ago

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma.

Cabozantinib inhibits tyrosine kinases, including vascular endothelial growth factor receptors 1, 2, and 3, MET, and AXL, which are implicated in the progression of hepatocellular carcinoma and the development of resistance...

Added 5 days ago

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Clinical trials

COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation (COLLISION)

The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.

Added 8 months ago

Enhanced Recovery After Surgery Program for Gastric Cancer: a Multi-center Study (ERASG1)

This study is aimed to evaluate the safety of applying enhanced recovery after surgery for gastric cancer.

Added 8 months ago

Study of Pembrolizumab (MK-3475) or Placebo Given With Best Supportive Care in Asian Participants With Previously Treated Advanced Hepatocellular Carcinoma (MK-3475-394/KEYNOTE-394)

The purpose of this study is to determine the efficacy and safety of pembrolizumab or placebo given with best supportive care (BSC) in Asian participants with previously systemically treated advanced hepatocellular carcinoma (HCC).

Added 5 days ago

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Blog Posts

Lauren McCracken

EAACI hot topics: Hereditary angioedema (HAE)

Posted 23 days ago

For many the fear of the unknown is a daunting thought, but particularly so for patients with HAE. Left untreated, this disease causes unpredictable recurrent severe swelling, typically of the limbs, face, intestinal tract and airway.

Alex Keen

ILC 2018 – Targetable pathways in liver disease: from identification to clinical application

Posted 3 months ago

A number of studies from the speakers at this year's ILC Basic Science Seminar are discussed here, focusing on targetable pathways in liver disease, covering pathway identification, potential drug targets and their clinical application.

Liam Farrell

Bad smells are good

Posted 1 year ago

Delicacy is not a virtue in this job.

CME

Obesity: clinical review

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
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The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test

Accrediting body
BMJ Learning - British Medical Learning
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90

Idiopathic constipation and nocturnal enuresis in childhood: a guide to management: putting NICE guidelines into practice

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
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90
Search all CME for Gastroenterology and hepatology