Data from multiple sources - Curated by Toby Galbraith - Last updated 13 April 2017

Latest news articles

Added 3 days ago Drug news

FDA accepts BLA from BMS for Opdivo (nivolumab) to treat hepatocellular carcinoma (liver cancer) after prior sorafenib therapy.

BMS has announced that the FDA accepted a supplemental Biologics License Application (sBLA) that seeks to extend the use of...

Added 3 days ago Drug news

Keytruda (pembrolizumab) is filed at FDA to treat advanced gastric or gastroesophageal junction adenocarcinoma.- Merck Inc.

Merck announced that the FDA has accepted for review a supplemental Biologics License Application (sBLA) for Keytruda (pembrolizumab), the company’s...

Added 6 days ago Drug news

Phase III FOURIER study of Repatha (evolocumab) shows effectiveness in reducing cardiovascular events- Amgen

Amgen announced new data from the Repatha (evolocumab) cardiovascular outcomes trial (FOURIER), which showed that Repatha consistently and safely reduced...

View all news articles

 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

Visit Fluid Management

Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

Visit Hyperammonaemia

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Visit Transplantation

 

Guidelines

American Association of Clinical Endocrinologists and American College of Endocrinology guidelines for management of dyslipidemia and prevention of atherosclerosis.

The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees.

Added 3 months ago

2016 ESC/EAS guidelines for the management of dyslipidaemias

Guidelines summarize and evaluate all available evidence on a particular issue at the time of the writing process, with the aim of assisting health professionals in selecting the best management strategies for an individual patient.

Added 3 months ago

EASL Clinical Practice Guidelines on the management of benign liver tumours

Benign liver tumours are a heterogeneous group of lesions with different cellular origins, as summarized by an international panel of...

Added 1 year ago

View all guidelines

Journal articles

Eluxadoline: A Review in Diarrhoea-Predominant Irritable Bowel Syndrome.

Eluxadoline (Truberzi) is an orally administered, minimally absorbed agent that acts locally in the gastrointestinal tract as a mixed µ-opioid receptor agonist and δ-opioid receptor antagonist.

Added 1 day ago

Bezlotoxumab: Could This B the Answer for Clostridium difficile Recurrence?

Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, and place in therapy of bezlotoxumab (BEZ), a novel monoclonal antibody against Clostridium difficile toxin B.

Added 5 days ago

The role of the high-affinity IgE receptor, FcepsilonRI, in eosinophilic gastrointestinal diseases.

Primary eosinophilic gastrointestinal diseases (EGIDs) are a heterogeneous group of diseases including eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis, eosinophilic enteritis...

Added 5 days ago

View all journal articles

Clinical trials

Sorafenib and Bavituximab Plus SBRT in Unresectable Hepatocellular Carcinoma

This study involves a course of radiation to up to 5 tumors in the participant's liver followed by systemic therapy (Treatment using substances that travel through the bloodstream, reaching and affecting cells all over the body).

Added 1 month ago

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

To assess the safety and tolerability of rovalpituzumab tesirine in subjects with specific delta-like protein 3-expressing advanced solid tumors.

Added 2 years ago

Prove of Concept Study, to Evaluate the Efficacy, Safety, and Tolerability of IBEROGAST in the Treatment of Bowel Troubles in Patients With Parkinson's Disease (PHYTOPARK)

The main objective of this study is to evaluate the efficacy of STW5 Iberogast, over a 28-day period, for the...

Added 2 years ago

View all clinical trials

Blog Posts

Liam Farrell

Bad smells are good

Posted 7 months ago

Delicacy is not a virtue in this job.

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Yuli Pramana

Choosing Between Endoscopic Sclerotherapy And Endoscopic Ligation For Esophageal Varices

Posted 2 years ago

Endoscopic Sclerotherapy (ES) and Endoscopic Ligation (EL) were accepted in the treatment of esophageal varices bleeding in patients with liver cirrhosis. EL seemed to be superior to ES. If EL was difficult then ES should be performed.

CME

Obesity: clinical review

Accrediting body
MIMS Learning - Monthly Index of Medical Specialities
Credits available
1
Registration required
1
Subscription fee
0

The diagnostic value of hyperammonemia induced by the non-ischemic forearm exercise test

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Idiopathic constipation and nocturnal enuresis in childhood: a guide to management: putting NICE guidelines into practice

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
View all CME