Latest news articles

Added 5 days ago Drug news

NICE recommends Onpattro to treat hereditary transthyretin-mediated amyloidosis

The National Institute for Health and Care Excellence (NICE) has recommended the use of Alnylam’s Onpattro (patisiran), after issuing a...

Added 10 days ago Drug news

Phase III study of napabucasin + nab-paclitaxel + gemcitabine for pancreatic cancer

Boston Biomedical/Sumitomo Dainippon announced that the Phase III CanStem111P study evaluating the safety and efficacy of investigational agent napabucasin plus...

Added 16 days ago Drug news

CHMP negative for Evenity for the treatment of severe osteoporosis

Amgen and UCB announced that the companies have been informed the Committee for Medicinal Products for Human Use (CHMP) of...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cushing's Syndrome

Cushing's Syndrome

Cushing’s syndrome shares symptoms such as hypertension, glucose intolerance and obesity with other common conditions – how can you confidently diagnose this rare disorder?

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Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction

Treatment with amiodarone is associated with changes in thyroid function tests, but also with thyroid dysfunction (amiodarone-induced hypothyroidism, AIH, and amiodarone-induced thyrotoxicosis, AIT).

Added 1 year ago

Guidelines on Male Hypogonadism

Androgens play a crucial role in the development and maintenance of male reproductive and sexual functions. Low levels of circulating androgens can cause disturbances in male sexual development, resulting in congenital abnormalities...

Added 4 years ago

The Hospital Management of Hypoglycaemia in Adults with Diabetes Mellitus

These guidelines, produced by the Joint British Diabetes Societies - Inpatient Care Group (JBDS-IP), are intended for use by clinicians and service commissioners to advise the treatment and hospital management of hypoglycaemia...

Added 5 years ago

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Journal articles

Type 1 and 2 diabetes mellitus: A review on current treatment approach and gene therapy as potential intervention.

Type 1 and type 2 diabetes mellitus is a serious and lifelong condition commonly characterised by abnormally elevated blood glucose levels due to a failure in insulin production or a decrease in insulin sensitivity and function.

Added 1 month ago

Efficacy of probiotic supplement for gestational diabetes mellitus: a systematic review and meta-analysis.

Background: Probiotic supplement might be beneficial for gestational diabetes mellitus. However, the results remained controversial. We conducted a systematic review and meta-analysis to explore the efficacy of probiotic...

Added 1 month ago

Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review.

Aim of the review: This article reviewed findings on medicinal plants with both anti-diabetic and anti-hypertensive effects reported in same experimental study to facilitate the development of dual-acting therapies against...

Added 1 month ago

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Clinical trials

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Disease

Multicenter, open-label, non-comparative study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in children and adolescent patients with Cushing's disease.

Added 28 days ago

Open-label Treatment in Cushing's Syndrome (OPTICS)

This is a long-term, OLE study of levoketoconazole in subjects with endogenous CS who have completed one or both parent studies or otherwise potentially qualify for this study, as defined in the eligibility criteria.

Added 28 days ago

Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

This phase 2 multicenter, open-label clinical trial will evaluate safety and efficacy of 4 weeks of oral seliciclib in patients with newly diagnosed, persistent, or recurrent Cushing disease.

Added 28 days ago

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Blog Posts

Adam Jeffery

Transforming Lives Through Technology: Diabetes

Posted 2 months ago

Right now, with a swipe or tap, I can tell you how many calories I’ve consumed, how far I’ve walked and how well I slept last night. However, digital health technology and its analytics have mixed reviews from the general public, some become obsessed wanting to know every macronutrient that goes into their body and others see it as just another gimmick. But what about those with chronic conditions like diabetes?

Robin Hewings

Diabetes Patients Must Be Better Educated About Their Condition

Posted 3 years ago

Not everyone is convinced that education courses help people look after their diabetes. And the GP I was chatting to a couple of months ago was one of them. He wasn’t sure they worked. People didn’t seem that interested and he wasn’t really sure what people would learn anyway.

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Step by step: how to diagnose and manage type 1 diabetes in adults in primary care

Accrediting body
BMJ Learning - British Medical Learning
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1
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90

Clinical pointers: Blood glucose control in type 2 diabetes

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90

Clinical pointers: recognising and managing acute complications of diabetes in adults

Accrediting body
BMJ Learning - British Medical Learning
Credits available
1
Registration required
1
Subscription fee
90
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