Data from multiple sources - Curated by Marshall Pearce - Last updated 06 June 2017

Latest news articles

Added 8 days ago Drug news

In a human abuse potential study, nasal administration Remoxy resulted in significantly lower abuse potential compared to immediate-release (IR) oxycodone.

Pain Therapeutics, Inc.announced positive results from a human abuse potential study of its late-stage drug candidate, Remoxy. 

Added 22 days ago Drug news

FDA extends PDUFA date for AndexXa for reversal of coagulation.- Portola Pharma

Portola Pharmaceuticals, Inc. announced that the FDA will extend its review of the Biologics License Application (BLA) for AndexXa (andexanet...

Added 28 days ago Advocacy news

National crossword puzzle day

Test your cruciverbalist credentials with our healthcare themed crossword!

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hyperammonaemia

Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

+ 2 more

Breakthrough Cancer Pain Learning Zone

Breakthrough Cancer Pain Learning Zone

Watch video highlights from the BeCOn OWN 2017 event, including expert opinion, patient experience and panel discussions in the Breakthrough Cancer Pain Learning Zone.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 10 months ago

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

The aim of this document is to provide practical, evidence-based guidelines for the diagnosis and treatment of HF. The principal...

Added 1 year ago

Acute coronary syndrome

This guideline provides recommendations for the management of patients with ACS within the first 12 hours and up to hospital discharge.

Added 3 months ago

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Journal articles

Early predictors of outcome after mild traumatic brain injury (UPFRONT): an observational cohort study.

Background: Mild traumatic brain injury (mTBI) accounts for most cases of TBI, and many patients show incomplete long-term functional recovery. We aimed to create a prognostic model for functional outcome...

Added 10 days ago

Reversal of dabigatran-associated major bleeding with activated prothrombin concentrate: A prospective cohort study.

The reversal of dabigatran-associated major bleeding can now be achieved with the antidote idarucizumab.

Added 28 days ago

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Clinical trials

Comparing Regional Anaesthesia to Systemic Analgesia to Decrease Post-Operative Delirium in Acute Hip Fracture Surgery (RASAPOD)

Post-operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and...

Added 2 years ago

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event (TRANSITION)

To explore two modalities of treatment initiation (Pre-discharge, and Post-discharge) with LCZ696 in HFrEF patients following stabilization after an ADHF...

Added 2 years ago

ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction (SF-STEMI)

The purpose of this study is to evaluate whether perioperative use of Shenfu Injection could reduce myocardial injury (enzymatic infarct...

Added 2 years ago

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Blog Posts

Laura Quittenden

What is AF or Atrial Fibrillation?

Posted 1 month ago

This week, from the 20th to the 26th November it is Global AF Awareness Week. Here we explore Atrial Fibrillation (also called AF or AFib), the most common heart rhythm disorder that can lead to stroke, blood clots, heart failure and other heart-related complications. Over 1 million people have been diagnosed with AF in the UK alone.  

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Antia Veiga Feijoo

Clinical Features and Treatment Of Acute Asthma Exacerbations

Posted 2 years ago

This post discusses clinical assessment and treatment of patients with acute asthma exacerbations.

CME

Dermatological emergencies in children

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MIMS Learning - Monthly Index of Medical Specialities
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Emergencies in dermatology

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MIMS Learning - Monthly Index of Medical Specialities
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Breaking bad news: a how to do it guide

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
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