Data from multiple sources - Curated by Toby Galbraith - Last updated 06 June 2017

Latest news articles

Added 20 hours ago Drug news

The FDA has found the resubmitted Biologics License Application (BLA) from Portola Pharmaceuticals Inc. relating to AndexXa (andexanet alfa) to be acceptable for review.

Portola Pharmaceuticals Inc. announced that the FDA has found its resubmitted Biologics License Application (BLA) for AndexXa (andexanet alfa) to...

Added 19 days ago Drug news

Phase III GiACTA study of Actemra (tocilizumab) in giant cell arteritis, is published in the New England Journal of Medicine.- Genentech/Roche.

Genentech a member of the Roche Group announced that data from the Phase III GiACTA study, which evaluated Actemra(tocilizumab) in...

Added 20 days ago Drug news

FDA gives complete response to filing of Ryanodex (dantrolene sodium) for exertional heat stroke- Eagle Pharmaceuticals

Eagle Pharmaceuticals has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) regarding its 505(b)(2) New...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Breakthrough Cancer Pain Learning Zone

Invitation to watch the online broadcast of the BeCOn OWN event 'Shifting paradigms in BTcP management' on June 16 2017.

Visit Breakthrough Cancer Pain Learning Zone


Hyperammonaemia

Hyperammonaemia can result in serious neurological damage or death. Could you recognise the signs and symptoms?

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Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more

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Guidelines

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 5 months ago

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

The aim of this document is to provide practical, evidence-based guidelines for the diagnosis and treatment of HF. The principal...

Added 1 year ago

BTS/ICS Guidelines for the Ventilatory Management of Acute Hypercapnic Respiratory Failure in Adults

The aim of the guideline is to draw attention to the evidence of suboptimal care in AHRF in the UK,...

Added 1 year ago

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Journal articles

Management of severe bleeding in patients treated with direct oral anticoagulants: an observational registry analysis.

The use of prothrombin complex concentrates and the role of plasma concentration of anticoagulants in the management of bleeding in patients treated with direct oral anticoagulants are still debated.

Added 30 days ago

Predictors of 30-day mortality in patients admitted to ED for acute heart failure.

Acute heart failure (AHF) is a leading cause of admission in emergency departments (ED).

Added 1 month ago

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Clinical trials

Comparing Regional Anaesthesia to Systemic Analgesia to Decrease Post-Operative Delirium in Acute Hip Fracture Surgery (RASAPOD)

Post-operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and...

Added 2 years ago

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event (TRANSITION)

To explore two modalities of treatment initiation (Pre-discharge, and Post-discharge) with LCZ696 in HFrEF patients following stabilization after an ADHF...

Added 2 years ago

ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction (SF-STEMI)

The purpose of this study is to evaluate whether perioperative use of Shenfu Injection could reduce myocardial injury (enzymatic infarct...

Added 2 years ago

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Blog Posts

Hugh Harvey

Metrics Madness

Posted 1 year ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

Antia Veiga Feijoo

Clinical Features and Treatment Of Acute Asthma Exacerbations

Posted 1 year ago

This post discusses clinical assessment and treatment of patients with acute asthma exacerbations.

Peter English

The advance decision not to attempt cardiopulmonary resuscitation

Posted 3 years ago

Decisions to start cardiopulmonary resuscitation (CPR), or to decide in advance to issue a "do not attempt (cardiopulmonary) resuscitation" (DNAR) notice have always been a hot topic in clinical medicine. It may have become even more so since a recent (June 2014) court decision. This post discusses some of the issues and legalities around DNAR decisions.

CME

Dermatological emergencies in children

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MIMS Learning - Monthly Index of Medical Specialities
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Emergencies in dermatology

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MIMS Learning - Monthly Index of Medical Specialities
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Breaking bad news: a how to do it guide

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Union of European Medical Specialists (via European Accreditation Council for CME)
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