Latest news articles

Added 4 days ago Drug news

Phase III DECLARE-TIMI 58 results for Farxiga show reduced risk of hospitalisation from CV events.- AstraZeneca.

AstraZeneca announced positive full results from the DECLARE-TIMI 58 cardiovascular (CV) outcomes trial (CVOT) for Farxiga (dapagliflozin) which showed that...

Added 4 days ago Drug news

PIONEER-HF trial of Entresto for heart failure published in NEJM.- Novartis.

Novartis announced results of the landmark PIONEER-HF trial showing that in-hospital initiation of Entresto (sacubitril/valsartan) tablets provided superior benefit compared...

Added 4 days ago Drug news

Phase III ODYSSEY OUTCOMES trial of Praluent shows fewer deaths from CV events-. Sanofi + Regeneron.

New analyses on mortality from the 18,924-patient phase III ODYSSEY OUTCOMES trial of Praluent (alirocumab), from Regeneron, shows it is...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

ESICM LIVES Highlights

ESICM LIVES Highlights

ESICM LIVES Congress 2018: Bringing you the latest news and insights from the 31st ESICM LIVES Congress, 20–24 October 2018 Paris, France.

Cardiovascular Metabolism Knowledge Centre

Cardiovascular Metabolism Knowledge Centre

The Cardiovascular Metabolism Knowledge Centre is an information hub providing expert insight into the management of hypertension and type 2 diabetes. This Knowledge Centre contains a wealth of scientific video content offering insights and opinion from some of the leading experts in the field.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Guidelines

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

The following Clinical Practice Guidelines (CPGs) represent the first CPGs on the management of decompensated cirrhosis.

Added 4 months ago

2018 ESC Guidelines for the diagnosis and management of syncope

The document aims to be patient-orientated and focused on therapy, and to reduce the risk of recurrence and the life-threatening consequences of syncope recurrence.

Added 9 years ago

Guidance document for prevention of Clostridium difficile infection in acute healthcare settings

This updated guideline provides a current review of the literature on interventions to control CDI in adult populations in acute healthcare settings and derives specific infection control recommendations.

Added 5 months ago

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Journal articles

Review of oritavancin for the treatment of acute bacterial skin and skin structure infections.

Objective: To assess critically oritavancin, a second-generation  lipoglycopeptide, for the treatment of Acute Bacterial Skin and Skin Structure Infections caused by susceptible Gram-positive bacteria...

Added 4 months ago

Effect of 0.9% Saline or Plasma-Lyte 148 as Crystalloid Fluid Therapy in the Intensive Care Unit on Blood Product Use and Postoperative Bleeding After Cardiac Surgery

To evaluate the effect of Plasma-Lyte 148 (PL-148) compared with 0.9% saline (saline) on blood product use and postoperative bleeding in patients admitted to the intensive care unit (ICU) following cardiac surgery.

Added 4 months ago

Direct oral anticoagulants (DOAC) – Management of emergency situations. Rationale and design of the RADOA-Registry

The worldwide increase in the aging population and the associated increase in the prevalence of atrial fibrillation and venous thromboembolism as well as the widespread use of direct oral anticoagulants (DOAC) have resulted...

Added 4 months ago

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Clinical trials

Comparing Regional Anaesthesia to Systemic Analgesia to Decrease Post-Operative Delirium in Acute Hip Fracture Surgery (RASAPOD)

Post-operative delirium is common after hip fracture surgery and is associated with increased length of hospital stay, delayed recovery and...

Added 3 years ago

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event (TRANSITION)

To explore two modalities of treatment initiation (Pre-discharge, and Post-discharge) with LCZ696 in HFrEF patients following stabilization after an ADHF...

Added 3 years ago

ShenFu Injection for Myocardial Protection in Patients With Acute ST Segment Elevation Myocardial Infarction (SF-STEMI)

The purpose of this study is to evaluate whether perioperative use of Shenfu Injection could reduce myocardial injury (enzymatic infarct...

Added 3 years ago

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Blog Posts

Alex Keen

ISICEM 2018 – The Sepsis Six and BUFALO

Posted 8 months ago

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

Laura Quittenden

What is AF or Atrial Fibrillation?

Posted 11 months ago

This week, from the 20th to the 26th November it is Global AF Awareness Week. Here we explore Atrial Fibrillation (also called AF or AFib), the most common heart rhythm disorder that can lead to stroke, blood clots, heart failure and other heart-related complications. Over 1 million people have been diagnosed with AF in the UK alone.  

Hugh Harvey

Metrics Madness

Posted 3 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Dermatological emergencies in children

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MIMS Learning - Monthly Index of Medical Specialities
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Emergencies in dermatology

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MIMS Learning - Monthly Index of Medical Specialities
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Breaking bad news: a how to do it guide

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Union of European Medical Specialists (via European Accreditation Council for CME)
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