Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 4 days ago Drug news

FDA approves Siliq (brodalumab) to treat moderate-to-severe plaque psoriasis.-Valeant Pharma Intl.

The FDA has approved Siliq (brodalumab) to treat adults with moderate-to-severe plaque psoriasis. Siliq is administered as an injection. Siliq...

Added 19 days ago Drug news

EU approves Votubia (everolimus) as adjunctive treatment for partial-onset seizures associated with tuberous sclerosis complex- Novartis

Novartis announced that the European Commission has approved Votubia (everolimus) dispersible tablets as an adjunctive treatment for patients aged two...

Added 23 days ago Drug news

Phase III pivotal trial results for SB 204 (nitric oxide) in treatment of acne vulgaris shows some benefits- Novan

Novan announced top-line results from the Company’s two, replicate Phase III pivotal clinical trials for SB 204 (nitric oxide) in...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Spontaneous Urticaria (CSU)

Use our patient case studies to discover how experts diagnose and treat chronic spontaneous urticaria

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IL-17A in Psoriasis

Experts discuss new targeted therapies for psoriasis at the European Association of Dermatology and Venereology (EADV) Congress 2015

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Psoriasis

See information on psoriasis pathophysiology, signs and symptoms, comorbidities, treatment options, and more

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Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

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Guidelines

Adalimumab for the treatment of adults with psoriasis

The severity of a person's psoriasis before and during treatment should be assessed by considering the redness, thickness and scaliness of the plaques, the area of the body involved, and how the condition...

Added 5 days ago

British Association of Dermatologists’ guidelines for biologic interventions for psoriasis 2009

Psoriasis is a common, chronic inflammatory skin disease which typically follows a relapsing and remitting course, and is associated with joint disease in approximately 25% of patients.

Added 5 days ago

Clinical practice guideline for an integrated approach to comorbidity in patients with psoriasis

To provide the dermatologist a guide focuses specifically on the diagnosis and management of the diseases most often found in patients with psoriasis.

Added 5 days ago

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Journal articles

Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis.

Interleukin-17A (IL-17A) is elaborated by the T helper 17 (T(H)17) subset of T(H) cells and exhibits potent proinflammatory properties in animal models of autoimmunity, including collagen-induced arthritis, experimental ...

Added 1 day ago

Anti-interleukin-17 monoclonal antibody ixekizumab in psoriasis.

The articles by Papp and colleagues and Leonardi and colleagues (both in the March 29 issue) attest to the growing interest in the therapeutic potential of agents such as ixekizumab and...

Added 1 day ago

Treatment with the interleukin-17a-blocking antibody secukinumab does not interfere with the efficacy of influenza and meningococcal vaccinations in healthy subjects: Results of an open-label, parallel-group, randomised single-center study

Our objective was to evaluate the efficacy of influenza and meningococcal vaccinations in healthy subjects exposed to the anti-interleukin-17A (IL-17A) monoclonal antibody (MAb) secukinumab.

Added 1 day ago

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Clinical trials

A Randomized, Double-blind, Placebo Controlled, Multicenter Regimen Finding Study of Subcutaneously Administered AIN457, Assessing Psoriasis Area and Severity Index (PASI) Response in Patients With Moderate to Severe Chronic Plaque-type Psoriasis

The purpose of the study is to determine whether, in patients with moderate to severe plaque-type psoriasis, AIN457 administered subcutaneously reduces the severity of psoriasis symptoms and the extent...

Added 15 hours ago

A Dose-Ranging And Efficacy Study of LY2439821 (An Anti-IL-17 Antibody) In Patients With Moderate-To-Severe Psoriasis

The safety of ixekizumab (LY2439821) and any side effects that might be associated with it....

Added 16 hours ago

A 12-Week Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Comparing the Efficacy and Safety of LY2439821 to Etanercept and Placebo in Patients With Moderate to Severe Plaque Psoriasis With a Long-Term Extension Period

This study will assess the safety and efficacy of ixekizumab (LY2439821), compared to etanercept and placebo in participants with moderate to severe chronic plaque psoriasis.

Added 4 days ago

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