Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 1 month ago Drug news

Vidas Brahms PCT Assay receives 510(k) clearance from FDA as diagnostic for respiratory tract infections, such as community-acquired pneumonia- BioMérieux

The FDA cleared the expanded use of the Vidas Brahms PCT Assay, from BioMérieux, to help health care providers determine...

Added 2 months ago Drug news

KRN 23 (monoclonal antibody) filed with the EU for the treatment of X-linked hypophosphatemia- Ultragenyx Pharmaceutical / Kyowa Kirin

Ultragenyx Pharmaceutical and Kyowa Kirin International announced that the European Medicines Agency has accepted for review the Marketing Authorisation Application...

Added 2 months ago Drug news

FDA refuses a filing application for Xaracoll (bupivacaine-collagen matrix) in pain treatment- Innocoll

Innocoll has received a Refusal to File letter from the United States Food and Drug Administration (FDA) for Xaracoll (bupivacaine-collagen...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients

Visit Oral Anticoagulation Reversal

 

Guidelines

Practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit: an executive summary. Society of Critical Care Medicine.

The development of practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit (ICU) setting for the purpose of guiding clinical practice.

Added 12 days ago

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 12 days ago

Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult.

Maintaining an optimal level of comfort and safety for critically ill patients is a universal goal for critical care practitioners.

Added 12 days ago

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Journal articles

The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: results of an exploratory study.

Survivors of acute respiratory distress syndrome (ARDS) are at risk for long-lasting cognitive decline due to hypoxemia, sepsis and/or psychological sequelae associated with aggressive supportive care in the intensive care unit (ICU).

Added 10 days ago

American Geriatrics Society abstracted clinical practice guideline for postoperative delirium in older adults.

The abstracted set of recommendations presented here provides essential guidance both on the prevention of postoperative delirium in older patients at risk of delirium and on the treatment of older surgical patients...

Added 11 days ago

Risk factors for delirium in intensive care patients: a prospective cohort study.

Delirium is a common complication in the intensive care unit. The attention of researchers has shifted from the treatment to the prevention of the syndrome necessitating the study of associated risk factors.

Added 11 days ago

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Clinical trials

Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation (DahLIA)

The primary aim of the DahLIA trial is to determine, in patients with ICU-associated delirium and agitation who are otherwise pathophysiologically stable (as defined), the number of ventilator-free hours...

Added 11 days ago

HalOPeridol Effectiveness in ICU delirium - the HOPE-ICU trial

This is a randomised placebo controlled, double blind, clinical effectiveness trial. It is designed to evaluate the effect of the early administration of haloperidol on duration of delirium in 142 mechanically...

Added 12 days ago

Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol (SLEAP)

The purpose of this study is to determine whether the use of both a nurse-driven sedation protocol and daily sedative interruption, compared with a sedation protocol alone, result in better outcomes for mechanically ventilated adults.

Added 12 days ago

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Blog Posts

Peter English

The advance decision not to attempt cardiopulmonary resuscitation

Posted 2 years ago

Decisions to start cardiopulmonary resuscitation (CPR), or to decide in advance to issue a "do not attempt (cardiopulmonary) resuscitation" (DNAR) notice have always been a hot topic in clinical medicine. It may have become even more so since a recent (June 2014) court decision. This post discusses some of the issues and legalities around DNAR decisions.

CME

Case Consults: Changing Paradigms in the Age of Biologics

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Treatment Optimisation in Chronic Lymphocytic Leukaemia

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
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FREE
View all CME