Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 1 day ago Drug news

EU approves change to authorisation for Repatha (evolocumab) to approve single-dose delivery option in dyslipidaemia treatment- Amgen

Amgen announced that the European Commission (EC) has adopted a decision to change the Repatha (evolocumab) marketing authorization, approving a...

Added 1 day ago Drug news

NICE confirms positive guidance on use of Galafold (migalastat) to treat Fabry disease.- Amicus Therapeutics

The National Institute for Health and Care Excellence (NICE) has confirmed final guidance endorsing the use of Galafold (migalastat) from...

Added 7 days ago Drug news

FDA approves Pro-Kinetic Energy cobalt chromium (CoCr) coronary stent system.- Biotronik

Biotronik announced it has received FDA approval for its Pro-Kinetic Energy cobalt chromium (CoCr) coronary stent system. The company gained...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hypogonadism

Epidemiology, pathophysiology, diagnosis/treatment guidelines, recent publication summaries and more

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Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients

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Type 2 Diabetes

View the latest epidemiology data, patient perspectives, ADA and EASD recommendations, treatment options and more

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Guidelines

2016 European Guidelines on cardiovascular disease prevention in clinical practice

The present guidelines represent an evidence-based consensus of the 6th European Joint Task Force  involving 10 professional societies.This document has...

Added 9 months ago

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

The aim of this document is to provide practical, evidence-based guidelines for the diagnosis and treatment of HF. The principal...

Added 9 months ago

Guideline on aspects of cancer-related venous thrombosis

The objective of this guideline is to provide healthcare professionals with clear guidance on the prevention and management of venous...

Added 1 year ago

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Journal articles

Repeated or intermittent levosimendan treatment in advanced heart failure: an updated meta-analysis

Advanced heart failure is a malignant disease characterized by a debilitating late course, with increasingly frequent hospitalisations and high rate of mortality.

Added 4 hours ago

The effects of levosimendan and OR-1896 on isolated hearts, myocyte-sized preparations and phosphodiesterase enzymes of the guinea pig

The concentration dependences of the Ca2+-sensitizing and the phosphodiesterase-inhibitory effects of levosimendan...

Added 5 hours ago

Levosimendan, a novel Ca2+ sensitizer, activates the glibenclamide-sensitive K+ channel in rat arterial myocytes

The electrophysiological effect of levosimendan, a novel Ca(2+)-sensitizing positive inotropic agent and vasodilator, was examined on rat mesenteric arterial myocytes using the patch clamp technique.

Added 9 hours ago

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Blog Posts

Dr Sarah Brewer

Would Your Hypertensive Patients Benefit From Garlic?

Posted 1 year ago

Would you consider recommending garlic tablets for patients with hypertension? Either instead of initiating monotherapy, or as an adjunct to current medication if they remained poorly controlled? The evidence for benefit is growing… 

Peter English

The advance decision not to attempt cardiopulmonary resuscitation

Posted 2 years ago

Decisions to start cardiopulmonary resuscitation (CPR), or to decide in advance to issue a "do not attempt (cardiopulmonary) resuscitation" (DNAR) notice have always been a hot topic in clinical medicine. It may have become even more so since a recent (June 2014) court decision. This post discusses some of the issues and legalities around DNAR decisions.

CME

Treatment Optimisation in Chronic Lymphocytic Leukaemia

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