Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 1 day ago Drug news

Data from ABSORB III study showed that Absorb Bioresorbable Vascular Stent was comparable in efficacy to the Xience metallic drug-eluting stent-Abbott

Abbott has announced that data from the ABSORB III U.S. pivotal trial showed that Absorb, Abbott's first-of-its-kind dissolving stent, had...

Added 1 day ago Drug news

RLX 030 (serelaxin) fails to meet endpoints of reduction of cardiovascular death or worsening heart failure in RELAX-AHF-2.- Novartis

Novartis announced results from the global Phase III RELAX-AHF-2 study investigating the efficacy, safety and tolerability of RLX 030 (serelaxin)...

Added 4 days ago Drug news

RE-CIRCUIT study of Pradaxa (dabigatran etexilate) shows less bleeding and fewer serious events in atrial fibrillation patients- Boehringer

New data from the RE-CIRCUIT study show a better safety profile for Pradaxa (dabigatran etexilate mesylate), from Boehringer, compared to...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Hypogonadism

Epidemiology, pathophysiology, diagnosis/treatment guidelines, recent publication summaries and more

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Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Type 2 Diabetes

View the latest epidemiology data, patient perspectives, ADA and EASD recommendations, treatment options and more

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Guidelines

Management of bleeding and coagulopathy following major trauma: an updated European guideline.

Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient. When these recommendations are implemented patient outcomes may be improved.

Added 17 days ago

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.

The aims of severe perioperative bleeding management are three-fold.

Added 17 days ago

Evidence-based management of anticoagulant therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines

High-quality anticoagulation management is required to keep these narrow therapeutic index medications as effective and safe as possible.

Added 17 days ago

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Journal articles

Selexipag: A Review in Pulmonary Arterial Hypertension.

Selexipag (Uptravi®) is an orally active, first-in-class, selective prostacyclin IP receptor agonist. Selexipag was approved recently in the EU for the long-term treatment of pulmonary arterial hypertension (PAH) in adult patients ...

Added 2 days ago

Selexipag for the treatment of pulmonary arterial hypertension.

Introduction: Targeted pulmonary vasoactive substances are the cornerstone of treatment in pulmonary arterial hypertension (PAH). Approved drugs act on various receptors and molecules within the pulmonary arteries ...

Added 2 days ago

Selexipag in Pulmonary Arterial Hypertension: Most Updated Evidence From Recent Preclinical and Clinical Studies.

Pulmonary arterial hypertension (PAH) is a relatively rare disease that, due to its chronic nature, has always been difficult to treat effectively. Selexipag is an oral prostacyclin (PGI2 ) agonist that was approved by ...

Added 2 days ago

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Clinical trials

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Added 10 days ago

Use of Dexmedetomidine in Children Undergoing Cardiac Surgery

The aim of the study is to evaluate the efficacy of dexmedetomidine in reducing the need for sedatives and analgesics in the immediate post-operative period in children who underwent surgical correction of...

Added 10 days ago

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Blog Posts

Dr Sarah Brewer

Would Your Hypertensive Patients Benefit From Garlic?

Posted 1 year ago

Would you consider recommending garlic tablets for patients with hypertension? Either instead of initiating monotherapy, or as an adjunct to current medication if they remained poorly controlled? The evidence for benefit is growing… 

Peter English

The advance decision not to attempt cardiopulmonary resuscitation

Posted 2 years ago

Decisions to start cardiopulmonary resuscitation (CPR), or to decide in advance to issue a "do not attempt (cardiopulmonary) resuscitation" (DNAR) notice have always been a hot topic in clinical medicine. It may have become even more so since a recent (June 2014) court decision. This post discusses some of the issues and legalities around DNAR decisions.

CME

Case Consults: Changing Paradigms in the Age of Biologics

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Treatment Optimisation in Chronic Lymphocytic Leukaemia

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Union of European Medical Specialists (via European Accreditation Council for CME)
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