Latest news articles

Added 4 days ago Drug news

ENGAGE AF-TIMI 48 trial of Lixiana shows reduced rates of intracranial haemorrhage for patients with atrial fibrillation.- Daiichi Sankyo.

Daiichi Sankyo Europe announced new sub-analysis data from the ENGAGE AF-TIMI 48 trial, which demonstrates that patients with atrial fibrillation...

Added 6 days ago Drug news

EU approves Repatha for adults with established atherosclerotic cardiovascular disease.-Amgen.

Amgen announced that the European Commission (EC) has approved a new indication in the Repatha (evolocumab) label for adults with...

Added 9 days ago Drug news

Analysis of ORION-1 Phase II trial of inclisiran shows reduction of atherogenic lipoproteins.-The Medicines Company.

The Medicines Company announced that the results of a pre-specified analysis of secondary endpoints from the ORION-1 Phase II study...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Acute and Advanced Heart Failure

Acute and Advanced Heart Failure

What are the most effective treatments for acute heart failure? Can you define advanced heart failure? Discover here...

+ 3 more

Fabry Disease

Fabry Disease

Explore the pathophysiology and treatment options for Fabry disease, a deficiency of the lysosomal enzyme alpha-galactosidase A

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

VTE is a condition in which a blood clot (thrombus) forms in a vein. It most commonly occurs in the...

Added 8 years ago

2018 ESC Guidelines for the diagnosis and management of syncope

The document aims to be patient-orientated and focused on therapy, and to reduce the risk of recurrence and the life-threatening consequences of syncope recurrence.

Added 8 years ago

BSH Guideline: management of thrombotic and haemostatic issues in paediatric malignancy

Venous thromboembolism (VTE) and bleeding are serious complications of cancer and its treatment. A recent survey of UK paediatric haematologists and oncologists identified a broad variety of practice in the management of issues...

Added 2 months ago

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Journal articles

Effects of levosimendan on mortality in patients with septic shock: systematic review with meta-analysis and trial sequential analysis.

Several studies have investigated a survival benefit for levosimendan treatment in patients with septic shock.

Added 8 days ago

Inotropic agents and vasodilator strategies for the treatment of cardiogenic shock or low cardiac output syndrome.

Cardiogenic shock (CS) and low cardiac output syndrome (LCOS) as complications of acute myocardial infarction (AMI), heart failure (HF) or cardiac surgery are life-threatening conditions.

Added 8 days ago

Haemodynamic effects of levosimendan in advanced but stable chronic heart failure.

Levosimendan improves haemodynamics in acute decompensated heart failure (HF).

Added 8 days ago

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Clinical trials

Multiple Cardiac Sensors for the Management of Heart Failure (MANAGE-HF)

The MANAGE-HF study is a multi-center, global, prospective, open label, multi-phase trial intended to evaluate the clinical efficacy of the HeartLogic heart failure diagnostic feature.

Added 7 months ago

Levosimendan Compassionate Use in Pediatric Patients With Advanced Decompensated Heart Failure

Open label study of levosimendan; planned comparison for effectiveness and safety to historic matched case controls from...

Added 1 year ago

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Added 1 year ago

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Blog Posts

Laura Quittenden

What is AF or Atrial Fibrillation?

Posted 6 months ago

This week, from the 20th to the 26th November it is Global AF Awareness Week. Here we explore Atrial Fibrillation (also called AF or AFib), the most common heart rhythm disorder that can lead to stroke, blood clots, heart failure and other heart-related complications. Over 1 million people have been diagnosed with AF in the UK alone.  

Professor Gerhard Pƶlzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 10 months ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Anticoagulation

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BJC Learning
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Step by step: A guide to diagnosing heart failure

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BMJ Learning - British Medical Learning
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90

Palliative care in patients with heart failure

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BMJ Learning - British Medical Learning
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90
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