Latest news articles

Added 7 days ago Drug news

Mallinckrodt plc announced two retrospective analyses providing health economic insights on use of Ofirmev for total knee arthroplasty.-

Mallinckrodt plc announced two retrospective analyses that provide health economic insights on use of Ofirmev (acetaminophen) injection – intravenous (IV)...

Added 13 days ago Drug news

European Commission approves Dzuveo to manage acute moderate to severe pain in medically monitored settings.- AcelRx Pharmaceuticals Inc.

AcelRx Pharmaceuticals, Inc. announced that the European Commission (EC) has approved Dzuveo (under development in the U.S. as Dsuvia) for...

Added 19 days ago Drug news

Phase II/III trial of IV CR 845 met statistical significance in patients undergoing abdominal surgeries.- Cara Therapeutics.

Cara Therapeutics announced positive top-line data from the adaptive Phase II/III trial of I.V. CR 845 in patients undergoing abdominal...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

+ 2 more

Pain, Agitation and Delirium (PAD) Management

Pain, Agitation and Delirium (PAD) Management

Discover the latest guidance on assessment and management of pain, agitation and delirium for patients requiring sedation.

+ 4 more

Oral Anticoagulation Reversal

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients.

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Guidelines

ECCO-ESCP Consensus on Surgery for Crohn’s Disease

The goal of this consensus initiated by the European Crohn’s and Colitis Organisation [ECCO] and European Society of Colo-Proctology [ESCP] was to establish European consensus guidelines for the surgical treatment of Crohn’s disease [CD].

Added 26 days ago

UK Commissioning guide: Massive Weight Loss Body Contouring

This document is about guidance for commissioning reconstructive procedures, post massive weight loss and is based on the best available evidence.

Added 1 month ago

Management of severe perioperative bleeding: Guidelines from the European Society of Anaesthesiology.

The aims of severe perioperative bleeding management are three-fold. First, preoperative identification by anamesis and laboratory testing of those patients for whom the perioperative bleeding risk may be increased...

Added 1 year ago

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Journal articles

Impact of Intravenous Acetaminophen on Lengths of Stay and Discharge Status after Total Knee Arthroplasty.

Postoperative pain remains difficult to control after total knee arthroplasty (TKA). While various modalities have been used, they have been associated with several side effects.

Added 7 days ago

Dexmedetomidine Based Sedation for Post-surgery Critically Ill Adults: A Meta-analysis of Randomized Controlled Trials.

Using dexmedetomidine (Dex) as a sedative agent may benefit the clinical outcomes of post-surgery patients. We reviewed randomized controlled trials to assess whether use of a Dex could improve the outcomes in post-surgery critically ill adults.

Added 5 months ago

Reversal of dabigatran-associated major bleeding with activated prothrombin concentrate: A prospective cohort study.

The reversal of dabigatran-associated major bleeding can now be achieved with the antidote idarucizumab.

Added 6 months ago

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Clinical trials

Comparison of Propofol and Dexmedetomidine to Treat Hyperactive and Mixed ICU Delirium - the Basel ProDex Randomized Trial

In this randomized study, the investigators aim to test the hypothesis that the reinstitution of a normal circadian rhythm by continuous infusions of dexmedetomidine compared to propofol between 8pm and 6am...

Added 1 year ago

Bioavailability and Pharmacokinetics of Intranasal Dexmedetomidine in Children

We aim to characterize the bioavailability and pharmacokinetics of dexmedetomidine after intranasal dosing employing pharmacometric methods in otherwise healthy 1 month to 11 years of age children scheduled...

Added 1 year ago

The Neuroprotective Effects of Dexmedetomidine During Brain Surgery

Dexmedetomidine (DEX) is a Alpha-2 specific agonist, is a common ICU sedation medication. In brain tumor resection craniotomy, it is proven to be effective in improving postoperative hypertension and...

Added 1 year ago

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Blog Posts

Alex Keen

ISICEM 2018 – The Sepsis Six and BUFALO

Posted 4 months ago

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

Professor Gerhard Pölzl

Acute and Advanced Heart Failure: new data, new studies, new opinions, new trends.

Posted 1 year ago

Professor Gerhard Pölzl focuses on the therapeutic options for acute and advanced heart failure.

Hugh Harvey

Metrics Madness

Posted 2 years ago

You shouldn't judge a book by its cover. That much is true, but it's also common sense not to judge a book by measuring the whiteness of its pages, or the amount of hamsters you can place on it. So why do we measure the fabulous NHS with nonsense metrics?

CME

Starting patients on oral anticoagulants in primary care: how to do it

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Union of European Medical Specialists (via European Accreditation Council for CME)
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Managing CSU and its comorbidities: from primary to secondary care

Managing CSU and its comorbidities: from primary to secondary care
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Union of European Medical Specialists (via European Accreditation Council for CME)
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FREE

Breaking bad news: a how to do it guide

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Union of European Medical Specialists (via European Accreditation Council for CME)
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