Data from multiple sources - Curated by Toby Galbraith - Last updated 04 January 2017

Latest news articles

Added 1 month ago Drug news

FDA approves expanded indication for OsteoCool RF Ablation System for palliative treatment of metastases in all bony anatomy- Medtronic

Medtronic announced that the FDA has cleared an expanded indication for the OsteoCool RF Ablation System. Originally cleared for use...

Added 1 month ago Drug news

FDA issues Complete Response Letter for CL 108 (hydrocodone, acetaminophen, promethazine), an investigational treatment for the management of pain.-Charleston Labs + Daiichi Sankyo.

Charleston Laboratories, Inc., and Daiichi Sankyo, Inc., confirmed that the FDA has issued a Complete Response Letter (CRL) regarding the...

Added 1 month ago Drug news

FDA and Health Canada approval for Machine-vision Image Guided Surgery (MIGS) system for spinal surgery.- 7D Surgical

7D Surgical announced that it has received both 510(k) clearance from the FDA and a medical device license from Health...

View all news articles

 

Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Cystic Fibrosis

View disease awareness information, treatment options and European Cystic Fibrosis Society best practice guidelines

Visit Cystic Fibrosis

Oral Anticoagulation Reversal

Experts discuss the use of non-vitamin K oral anticoagulants in the treatment and prevention of stroke, deep vein thrombosis and pulmonary embolism in atrial fibrillation patients

Visit Oral Anticoagulation Reversal

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

Visit Transplantation

 

Guidelines

Practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit: an executive summary. Society of Critical Care Medicine.

The development of practice parameters for intravenous analgesia and sedation for adult patients in the intensive care unit (ICU) setting for the purpose of guiding clinical practice.

Added 11 days ago

Comfort and patient-centred care without excessive sedation: the eCASH concept.

We propose an integrated and adaptable approach to improve patient care and clinical outcomes through analgesia and light sedation, initiated early during an episode of critical illness and as a priority of care.

Added 11 days ago

Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult.

Maintaining an optimal level of comfort and safety for critically ill patients is a universal goal for critical care practitioners.

Added 11 days ago

View all guidelines

Journal articles

Risk factors for delirium in intensive care patients: a prospective cohort study.

Delirium is a common complication in the intensive care unit. The attention of researchers has shifted from the treatment to the prevention of the syndrome necessitating the study of associated risk factors.

Added 10 days ago

Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial.

Delirium is a postoperative complication that occurs frequently in patients older than 65 years, and presages adverse outcomes.

Added 10 days ago

A new approach to the prevention and treatment of delirium in elderly patients in the intensive care unit.

The pronounced prevalence of delirium in geriatric patients admitted to the intensive care unit (ICU) and its increased morbidity and mortality is a well-established phenomenon.

Added 10 days ago

View all journal articles

Clinical trials

Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation (DahLIA)

The primary aim of the DahLIA trial is to determine, in patients with ICU-associated delirium and agitation who are otherwise pathophysiologically stable (as defined), the number of ventilator-free hours...

Added 10 days ago

HalOPeridol Effectiveness in ICU delirium - the HOPE-ICU trial

This is a randomised placebo controlled, double blind, clinical effectiveness trial. It is designed to evaluate the effect of the early administration of haloperidol on duration of delirium in 142 mechanically...

Added 11 days ago

Daily Sedative Interruption in Critically Ill Patients Being Managed With a Sedation Protocol (SLEAP)

The purpose of this study is to determine whether the use of both a nurse-driven sedation protocol and daily sedative interruption, compared with a sedation protocol alone, result in better outcomes for mechanically ventilated adults.

Added 11 days ago

View all clinical trials

CME

Case Consults: Changing Paradigms in the Age of Biologics

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
FREE

Treatment Optimisation in Chronic Lymphocytic Leukaemia

Accrediting body
Union of European Medical Specialists (via European Accreditation Council for CME)
Credits available
1
Registration required
1
Subscription fee
FREE
View all CME