37,688 Results

Prognostic Biomarkers Used for Localised Prostate Cancer Management: A Systematic Review.

Objective: This systematic review by the Intergroupe Coopérateur Francophone de Recherche en Onco-urologie (ICFuro) analysed new evidence on the analytical validity and clinical validity and utility of six prognostic...

The microbiome in prostate inflammation and prostate cancer.

Background: The human microbiome may influence prostate cancer initiation and/or progression through both direct and indirect interactions. To date, the majority of studies have focused on direct interactions including...

Androgen-targeted therapy in men with prostate cancer: evolving practice and future considerations.

Background: Androgen deprivation therapy (ADT) is foundational in the management of advanced prostate cancer (PCa) and has benefitted from a recent explosion in scientific advances. These include approval of new therapies that...

FDA approves Skyrizi for plaque psoriasis

 Added 1 day ago

AbbVie announced that the FDA approved Skyrizi (risankizumab-rzaa), an interleukin-23 (IL-23) inhibitor, for the treatment of moderate to severe plaque...

Development of Ajovy is discontinued in cluster headaches

 Added 1 day ago

Teva Pharmaceutical provided an update that the Company is discontinuing the clinical development program for use of Ajovy (fremanezumab) in...

FDA approves LOTUS Edge Aortic Valve System to treat severe aortic stenosis

 Added 1 day ago

Boston Scientific Corporation announced it has received FDA approval for the LOTUS Edge Aortic Valve System. Delivered via a minimally-invasive...

Effectiveness of Biologic and Conventional Systemic Therapies in Adults with Chronic Plaque Psoriasis in Daily Practice: A Systematic Review.

The efficacy of biologic or conventional systemic therapies for psoriasis has been shown in randomized controlled trials. Effectiveness, however, has been studied in daily practice cohorts, and no aggregation of effectiveness data...

Long-term efficacy of novel therapies in moderate-to-severe plaque psoriasis: a systematic review and network meta-analysis of PASI response.

Background: Patients with moderate‐to‐severe psoriasis require long‐term treatment, yet few trials compare outcomes beyond a short‐term induction period. Quantitative comparisons of long‐term outcomes in patients with...

FDA approves TransPyloric Shuttle device for obesity

 Added 2 days ago

BAROnova announced that the FDA has approved the TransPyloric Shuttle (TPS) Device, a non-surgical weight loss solution for adult individuals...

Five-year study shows SRT-100 benefits patients with non-melanoma skin cancer

 Added 2 days ago

Sensus Healthcare announced topline results from a five-year retrospective study of non-melanoma skin cancer (NMSC) patients treated with Superficial Radiation...

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