Horizons

Opinion & insight from our Clinical Steering Group

Horizons, led by a team of experts from our Clinical Steering Group, is a series of scientific articles which take a deep dive into the emerging trends in the healthcare landscape, kickstarting a dialogue about how novel treatments and strategies could change prospects for patients in the near future.

We're discussing new treatments, strategies and devices, and how they are set to disrupt healthcare practices in the coming years. Some of the topics we'll be tackling include:

  • Antibody-drug conjugates

  • Immuno-oncology

  • Cardiology devices

  • Oral proteasome inhibitors in multiple myeloma

  • PARP inhibitors

  • Alzheimer's disease

  • CAR-T therapies in oncology

Looking to the horizon - Breakthrough drugs and treatments

Marshall Pearce

How close are we to a disease-modifying treatment for Alzheimer’s?

Posted 7 months ago

Alzheimer’s disease is a snowballing problem, one that is currently without a convincing solution. The progressive decline in cognitive function seen in patients with Alzheimer’s disease is associated strongly with plaques formed of amyloid beta in the brain, creating neurofibrillary tangles and leading to neuronal destruction. While some treatments improve cognition in the short-term, current therapeutic options are unable to modify or slow the disease process.

Penny Staton

Improving non-alcoholic steatohepatitis care – is the finishing line in sight?

Posted 9 months ago

An intense race is going on right now in non-alcoholic steatohepatitis (NASH) research. A number of significant players within the pharmaceutical and biotechnology sectors are competing to develop the first major therapeutic advance in treatment for this neglected condition. But should we consider it more of a relay race? Could improved diagnosis, disease assessment and even combination therapy be the key to victory over this increasingly prevalent disease?

Marshall Pearce

Left ventricular assist devices – A viable therapeutic option for heart failure?

Posted 1 year ago

Alongside a pharmacological strategy to aid myocardial recovery, LVADs may prove to have a significant role to play in the ever-growing problem of heart failure. Although LVADs are not new onto the scene, the advance of technology – smaller, more efficient devices with better reliability and potentially transcutaneous power transfer – means we may be on the cusp of seeing many more deployed to tackle heart failure.

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