The adsorption of thrombin to fibrin during clotting defines “Antithrombin I” activity. We confirmed that thrombin generation in afibrinogenemic or in Reptilase defibrinated normal plasma was higher than in normal plasma.
In 14 consecutive patients undergoing cardiopulmonary bypass for coronary bypass surgery the time course of coagulation and fibrinolysis markers were measured, e. g. plasma levels of thrombin-antithrombin III (TAT) complexes...
Mitsubishi Tanabe Pharma's (MTP) has launched the direct thrombin inhibitor Exembol (argatroban) in the UK for the treatment of adult...
Baxter International Inc. announced an agreement to acquire two hemostat and sealant products from Mallinckrodt plc : Recothrom Thrombin topical...
Diffuse bleeding after chest wall and spine resection represents a major problem in General Thoracic Surgery. Several fibrin sealants (FS)...
Discover thrombin generation and thromboelastometry in monitoring the in-vitro reversal of warfarin: a comparison between 3-factor PCC 4-factor PCC.
Discover in this publication digest the recommendations for monitoring and reversal of newer anticoagulants and how they have evolved in recent years.
We describe a patient with congenital afibrinogenemia who showed elevated prothrombin activation fragments (F1+2) indicating increased thrombin formation.