Data from FDA (Food and Drug Administration, USA) - Curated by EPG Health - Last updated 07 February 2017
PRECAUTIONS: In elderly and debilitated patients,
In general, the concomitant administration of chlordiazepoxide HCI and
If such combination therapy seems indicated,
The usual precautions in treating
The usual precautions are indicated when chlordiazepoxide HCI capsules are used in the treatment of
In view of isolated reports associating
Information for Patients: To
Drowsiness, ataxia and
In few instances syncope has been reported.
Changes in EEG patterns (low-voltage
Blood dyscrasias (including agranulocytosis), jaundice and hepatic
When chlordiazepoxide treatment is protracted, periodic
DOSAGE AND ADMINISTRATION: Because of the
The dosage, therefore, should be individualized for maximum
If used as preoperative medication, 50 to 100 mg IM * one hour prior to surgery.
CHILDREN Usual Daily Dose Because of the
Since clinical experience in
5 mg, 2 to 4 times daily (may be
If the drug is administered orally, the suggested initial dose is 50 to 100 mg, to be followed by repeated doses as
* See package insert for Sterile Chlordiazepoxide Hydrochloride.
Management of Overdosage: Manifestations of chlordiazepoxide overdosage includes somnolence,
Respiration, pulse and
Intravenous fluids should be administered and an
There have been occasional reports of excitation in patients following chlordiazepoxide overdosage; if this occurs barbiturates should not be used.
As with the management of intentional overdosage with any drug, it should be borne in mind that multiple agents may have been ingested.
Flumazenil, a specific benzodiazepine receptor
Prior to the administration of flumazenil, necessary measures should be instituted to
Flumazenil is intended as an adjunct to, not as a substitute for,
Patients treated with flumazenil should be monitored for resedation, respiratory
|Date Last Revised||01-01-2010|
|Type||HUMAN PRESCRIPTION DRUG|
|Marketing authorisation holder||PD-Rx Pharmaceuticals, Inc.|