Vinblastine Sulfate 1 mg/ml Injection
Vinblastine sulfate is a cytotoxic drug that arrests cell growth at the metaphase. Its actions are more pronounced on the rapidly dividing cell than on the normal cell. It appears to act, like vincristine, by binding to the microtubular proteins of the mitotic spindle, preventing polymerisation. Information available at present suggests that vinblastine sulfate may be useful, either alone or in combination with other oncolytic drugs, for the treatment of: Hodgkin's disease; non-Hodgkin's lymphoma; carcinoma of the breast; methotrexate-resistant choriocarcinoma; renal cell carcinoma; testicular teratoma and seminoma; histiocytosis X. Other neoplasms occasionally show a marked response to vinblastine sulfate, but less frequently than the more susceptible conditions listed above.