Latest news articles

Added 26 days ago Drug news

FDA approves Taltz to treat ankylosing spondylitis

Eli Lilly and Company announced that the FDA has approved Taltz (ixekizumab) injection 80 mg/mL for the treatment of adults...

Added 3 months ago Drug news

Nektar Therapeutics announces formation of Inheris Biopharma Inc., a CNS focused company

Nektar Therapeutics announced the formation of Inheris Biopharma, Inc., a wholly-owned subsidiary of Nektar and a CNS-focused company. Inheris will...

Added 7 months ago Drug news

Top-line results From phase III study of tanezumab in chronic low back pain. Eli Lilly + Pfizer

Pfizer Inc. and Eli Lilly and Company announced positive top-line results from a Phase III study evaluating tanezumab in patients...

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An Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Low back pain and sciatica in over 16s: assessment and management

This guideline covers assessing and managing low back pain and sciatica in people aged 16 and over.

Added 10 years ago

Management of chronic pain

This guideline provides recommendations based on current evidence for best practice in the assessment and management, in non-specialist settings, of adults with chronic non-malignant pain...

Added 5 years ago

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Journal articles

No increased incidence of inflammatory bowel disease among secukinumab-treated patients with moderate to severe psoriasis, psoriatic arthritis, or ankylosing spondylitis: data from 14 phase 2 and phase 3 clinical studies.

Secukinumab (SEC), a fully human anti–interleukin-17A monoclonal antibody, has been evaluated and approved for the treatment of moderate to severe psoriasis (PsO), active psoriatic arthritis (PsA) and active ankylosing spondylitis (AS).

Added 2 years ago

Regulation of peripheral classical and non-classical monocytes on infliximab treatment in patients with rheumatoid arthritis and ankylosing spondylitis.

Objective: To investigate the regulatory effect of tumour necrosis factor (TNF) blockade with infliximab on the distribution of peripheral blood...

Added 3 years ago

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Clinical trials

A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis (COAST-W)

The main purpose of this study is to evaluate the efficacy and safety of ixekizumab in tumor necrosis factor (TNF) inhibitor-experienced participants with radiographic axial spondyloarthritis (rad-axSpA).

Added 1 year ago

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Adam Jeffery

What is Overdiagnosis?

Overdiagnosis is the diagnosis of disease that will cause neither morbidity nor mortality during a patient’s lifetime. Doctors are trained to listen, examine, test, diagnose and treat patients, but we are not warned of the possible dangers of “diseases”, the diagnosis of which will not benefit the patient and may also lead to harm. I would argue that the Hippocratic oath, in particular “Primum non nocere” (first, do no harm) should be at the forefront of every clinician’s mind when seeing patients.


Diabetes prevention, back pain and PSA testing: clinical update April 2016

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