Latest news articles

Added 11 months ago Drug news

FDA approves expanding indication of the Elecsys BRAHMS PCT assay to aid antibiotic treatment in infection.- Roche.

Roche announced that it has received clearance from the FDA for the expanded use of its Elecsys BRAHMS PCT assay...

Added 1 year ago Drug news

Giapreza filed with EMA for septic shock with hypotension.- La Jolla Pharmaceutical.

La Jolla Pharmaceutical announced that the Marketing Authorisation Application (MAA) for Giapreza (angiotensin II) Injection for Intravenous Infusion was validated...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Fibrinogen Deficiency in Bleeding

Fibrinogen Deficiency in Bleeding

Fibrinogen is important for blood clot formation and breakdown. It is the first coagulant factor to be reduced to critical levels during massive trauma, cardiac surgery and postpartum haemorrhage that involve excessive bleeding. Persistent fibrinogen deficiency can lead to bleeding complications and an increased risk in mortality. This learning zone looks at both congenital and acquired fibrinogen deficiencies including indications and techniques for diagnosis, trigger level for treatment and treatment options.

Fluid Management

Fluid Management

Are you up-to-date with the latest evidence of effective procedures for fluid management?

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Guidelines

Consensus on circulatory shock and hemodynamic monitoring

Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate.

Added 4 years ago

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

The recommendations in this document are intended to provide guidance for the clinician caring for a patient with severe sepsis or septic shock.

Added 6 years ago

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Journal articles

Aggressive fluid management in the critically ill: Pro.

This review is a “Pro-Con” discussion about the optimal fluid volume in critically ill patients in the intensive care unit (ICU). This article argues that fluids should be aggressively managed in critically ill patients.

Added 3 months ago

Shock Etiologies and Fluid Management in Liver Failure.

Liver failure can occur in patients with or without underlying chronic liver disease (mainly cirrhosis) and is, respectively, termed acute on chronic liver failure or acute liver failure (ALF). In both cases, it is associated with...

Added 3 months ago

Effects of levosimendan on mortality in patients with septic shock: systematic review with meta-analysis and trial sequential analysis.

Several studies have investigated a survival benefit for levosimendan treatment in patients with septic shock.

Added 1 year ago

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Clinical trials

Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock

The role of albumin in sepsis has been controversial for decades. Although hypoalbuminemia has been associated with worse outcomes in sepsis, definitive evidence does not exist that replacing albumin in these patients improves outcomes.

Added 3 months ago

Altering Sedation Paradigms to Improve Brain Injury and Survival in Severe Sepsis

Ventilated ICU patients frequently have sepsis and the majority have delirium, a form of brain dysfunction that is an independent predictor of increased risk of dying, length of stay, costs, and prolonged cognitive...

Added 2 years ago

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Alex Keen

Alex studied Biological Sciences at university before joining EPG Health in January 2017, where he works as a digital content manager and editor.

In his spare time, Alex enjoys relaxing with a cool pint in the company of good friends. 

ISICEM 2018 – The Sepsis Six and BUFALO

At nearly 30 million annual cases and 6 million deaths globally, sepsis is one of the world’s biggest killers. The Sepsis Six and BUFALO aim to speed up the time from sepsis diagnosis to effective treatment by using 6 simple steps, with the aim to improve outcomes across the globe. 

CME

Sepsis case study

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MIMS Learning - Monthly Index of Medical Specialities
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