Effects of levosimendan on mortality in patients with septic shock: systematic review with meta-analysis and trial sequential analysis.
Several studies have investigated a survival benefit for levosimendan treatment in patients with septic shock.
Goal-directed therapy has been used for severe sepsis and septic shock in the intensive care unit.
After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septicshock, three multicenter trials (ProCESS, ARISE, and ProMISe) showed no benefit.
Impact of intravenous fluid composition on outcomes in patients with systemic inflammatory response syndrome
Intravenous (IV) fluids may be associated with complications not often attributed to fluid type. Fluids with high chloride concentrations such as 0.9 % saline have been associated with adverse outcomes in surgery and critical care.
Bone lesions from multiple myeloma may lead to pathological fracture of the proximal femur, requiring either fixation or arthroplasty. Little is known about the impact of multiple myeloma on hip fracture care.
Fluid resuscitation is the cornerstone of sepsis treatment. However, whether balanced or unbalanced crystalloids or natural or synthetic colloids confer a survival advantage is unclear.
Development of a mortality prediction formula due to sepsis/severe sepsis in a medical intensive care unit.
BACKGROUND: Although sepsis is one of the leading causes of mortality in hospitalized patients, information regarding early predictive factors for...
Repeated Emergency Department Visits Among Children Admitted With Meningitis or Septicemia: A Population-Based Study
Study objective: Early diagnosis of children with meningitis or septicemia remains a significant challenge in emergency medicine. We seek to...
The impact of hospital-onset Clostridium difficile infection on outcomes of hospitalized patients with sepsis
Background:Most prior studies that have addressed this issue lacked adequate matching to controls, suffered from small sample size, or failed...
Hospital admission rates for meningitis and septicaemia caused by Haemophilus influenzae, Neisseria meningitidis, and Streptococcus pneumoniae in children in England over five decades: a population-based observational study
Background:Infection with Haemophilus influenzae, Neisseria meningitidis, and StreptococcuS pneumoniae causes substantial mortality and long–term morbidity in children. We know of...