Data from multiple sources - Curated by EPG Health - Last updated 06 June 2017

Latest news articles

Added 7 days ago Drug news

Data analysis shows higher rates of mucosal healing with Entyvio in ulcerative colitis and Crohn's disease.- Takeda.

Takeda Pharmaceutical announced new real-world data evaluating the comparative effectiveness of Entyvio (vedolizumab) and tumor necrosis factor-alpha (TNFalpha)-antagonist therapy in...

Added 10 days ago epgonline.org announcements

New inflammatory bowel disease (IBD) Knowledge Centre

A tool for healthcare professionals who treat inflammatory bowel disease (IBD) has launched on epgonline.org.

Added 14 days ago Drug news

PDUFA review date extended to 13 May 2018 for Plenvu bowel cleansing preparation.- Salix/Valeant + Norgine B.V.

Salix Pharmaceuticals, Ltd ,a wholly owned subsidiary of Valeant Pharmaceuticals International, Inc., and its partner Norgine B.V. have received notice...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Inflammatory Bowel Disease Knowledge Centre

Inflammatory Bowel Disease Knowledge Centre

The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and unmet needs and the underlying inflammatory processes that drive IBD, considering some of the key inflammatory pathways.

Transplantation

Transplantation

See information on best practice in solid organ transplantation, and expert discussions on related hot topics.

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Guidelines

The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease

Trying to conceive and being pregnant is an emotional period for those involved. In the majority of patients suffering from...

Added 2 years ago

European Consensus on the Diagnosis and Management of Iron Deficiency and Anaemia in Inflammatory Bowel Diseases

The goal of this consensus initiated by the European Crohn’s and Colitis Organisation [ECCO] was to establish European consensus guidelines...

Added 3 years ago

European evidence based consensus on surgery for ulcerative colitis

The goal of this consensus initiated by the European Crohn's and Colitis Organisation (ECCO) was to establish European consensus guidelines...

Added 3 years ago

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Journal articles

Novel Therapies and Treatment Strategies for Patients with Inflammatory Bowel Disease.

This article reviews current treatment options and strategies and provides an update on the status of drug development programs of new therapeutic agents for inflammatory bowel diseases (IBD).

Added 8 days ago

Review article: predictors of response to vedolizumab and ustekinumab in inflammatory bowel disease.

Aim: To summarise the current data on predictors of response to vedolizumab and ustekinumab in IBD patients.

Added 8 days ago

Safety, efficacy and pharmacokinetics of vedolizumab in patients with simultaneous exposure to an anti-tumour necrosis factor.

Aim: To explore outcomes of patients co-exposed to anti-TNF and vedolizumab.

Added 8 days ago

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Clinical trials

The Impact of Anti-TNF Exposure on Vedolizumab Effectiveness

Vedolizumab is a new medication being used for the treatment of Crohn's disease and Ulcerative colitis. It works by blocking specific white blood cells (alpha 4-beta7 lymphocytes) from migrating to areas of inflammation in...

Added 8 days ago

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy

To determine the efficacy and safety of multiple doses of ABT-494 in subjects with moderately to severely active Crohn's Disease with a history of inadequate response to or intolerance to Immunomodulators or anti-Tumor Necrosis Factor...

Added 8 days ago

Personalising Anti-TNF Therapy in Crohns Disease (PANTS)

The primary objective of this study is to investigate the mechanisms that underlie primary non-response (PNR), loss of response (LOR) and adverse drug reactions (ADRs) to anti-TNF drugs in patients with active luminal Crohn's disease.

Added 8 days ago

Search all clinical trials for Regional enteritis and ulcerative colitis