Latest news articles

Added 18 days ago Drug news

FDA accepts NDA for fedratinib to treat myelofibrosis

Celgene Corporation announced the FDA has accepted the company’s New Drug Application (NDA) for fedratinib and granted a Priority Review....

Added 1 month ago Drug news

CTI BioPharma Corp. will withdraw its application (MAA) to EMA for pacritinib as a treatment for myelofibrosis.

CTI BioPharma Corp. announced that the Company will withdraw its European Marketing Authorization Application (MAA) for pacritinib as a treatment...

Added 6 months ago Drug news

Sierra Oncology, Inc. announces it has acquired momelotinib from Gilead Sciences. for the treatment of myelofibrosis.

Sierra Oncology, Inc. announced it has acquired the drug candidate momelotinib from Gilead Sciences. Momelotinib has been investigated in two...

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Learning Zones

An epgonline.org Learning Zone (LZ) is an area of the site dedicated to providing detailed self-directed medical education about a disease, condition or procedure.

Chronic Lymphocytic Leukaemia (CLL)

Chronic Lymphocytic Leukaemia (CLL)

Refine your knowledge of chronic lymphocytic leukaemia (CLL) with information on pathophysiology, diagnosis, treatment options and more

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Biosimilars in Oncology Knowledge Centre

Biosimilars in Oncology Knowledge Centre

What are biologics and how do they differ from small molecule medicines? Discover more about their development, as well as the manufacturing and regulatory processes in the Biosimilars in Oncology Knowledge Centre.

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Guidelines

Philadelphia chromosome-negative chronic myeloproliferative neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Philadelphia chromosome negative chronic myeloproliferative neoplasms include polycythaemia vera, essential thrombocythaemia and primary myelofibrosis. The new ESMO Clinical Practice Guidelines...

Added 3 years ago

Use of JAK inhibitors in the management of myelofibrosis: a revision of the British Committee for Standards in Haematology Guidelines for Investigation and Management of Myelofibrosis 2012

Guidelines for myelofibrosis were produced in 2012 (Reilly et al, 2012), but since then Ruxolitinib, a JAK1/JAK2 inhibitor, has been approved for use in the European Union and highly prevalent mutations in the Calreticulin gene (CALR)...

Added 4 years ago

Guideline for the diagnosis and management of myelofibrosis

The purpose of this guideline is to provide a practical, rather than a research, approach to the diagnosis, investigation and management of patients with primary myelofibrosis, as well as post-polycythaemic myelofibrosis (post-PV MF) and...

Added 6 years ago

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Journal articles

Heat-stable carbetocin versus oxytocin to prevent hemorrhage after vaginal birth

Postpartum hemorrhage is the most common cause of maternal death. Oxytocin is the standard therapy for the prevention of postpartum hemorrhage , but it requires cold storage, which is not available in many countries.

Added 8 months ago

Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network.

Ascertainment of cases and disease classification is an acknowledged problem for epidemiological research into haematological malignancies.

Added 1 year ago

Erythrocytosis following testosterone therapy.

A rapid increase in awareness of androgen deficiency has led to substantial increases in prescribing of testosterone therapy (TTh), with benefits of improvements in mood, libido, bone density, muscle mass, body composition, energy, and cognition.

Added 1 year ago

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Clinical trials

Carbetocin RTS for preventing postpartum haemorrhage: a randomized non-inferiority controlled trial (CHAMPION)

A phase III, randomized, double-blind, active, controlled, multinational, multicentre, non-inferiority trial using carbetocin room temperature stable (RTS) for the prevention of postpartum...

Added 8 months ago

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